Evidence map›Paper›PMID 35867831›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Declines in prevalence alter the optimal level of sexual investment for the malaria parasite

Angela M Early, Flavia Camponovo, Stéphane Pelleau, Gustavo C Cerqueira, Yassamine Lazrek, Béatrice Volney, Manuela Carrasquilla, Benoît de Thoisy, Caroline O Buckee, Lauren M Childs and 2 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Temporal and spatial dynamics ofbioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Angela M EarlyInfectious Disease and Microbiome Program, Broad Institute, Cambridge, MA 02142.ORCID 0000-0002-3169-2324
Flavia CamponovoCenter for Communicable Disease Dynamics, Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA 02115.ORCID 0000-0002-9762-851X
Stéphane PelleauCentre National de Référence du Paludisme, World Health Organization Collaborating Center for Surveillance of Antimalarial Drug Resistance, Institut Pasteur de la Guyane, 97300 Cayenne, French Guiana.ORCID 0000-0002-7070-2177
Gustavo C CerqueiraInfectious Disease and Microbiome Program, Broad Institute, Cambridge, MA 02142.
Yassamine LazrekCentre National de Référence du Paludisme, World Health Organization Collaborating Center for Surveillance of Antimalarial Drug Resistance, Institut Pasteur de la Guyane, 97300 Cayenne, French Guiana.
Béatrice VolneyCentre National de Référence du Paludisme, World Health Organization Collaborating Center for Surveillance of Antimalarial Drug Resistance, Institut Pasteur de la Guyane, 97300 Cayenne, French Guiana.
Manuela CarrasquillaDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115.ORCID 0000-0002-7953-4376
Benoît de ThoisyLaboratoire des Interactions Virus Hôtes, Institut Pasteur de la Guyane, 97306 Cayenne, French Guiana.ORCID 0000-0002-8420-5112
Caroline O BuckeeCenter for Communicable Disease Dynamics, Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA 02115.ORCID 0000-0002-8386-5899
Lauren M ChildsDepartment of Mathematics, Virginia Tech, Blacksburg, VA 24061.ORCID 0000-0003-3904-3895
Lise MussetCentre National de Référence du Paludisme, World Health Organization Collaborating Center for Surveillance of Antimalarial Drug Resistance, Institut Pasteur de la Guyane, 97300 Cayenne, French Guiana.ORCID 0000-0003-0215-4110
Daniel E NeafseyInfectious Disease and Microbiome Program, Broad Institute, Cambridge, MA 02142.ORCID 0000-0002-1665-9323
Institut Pasteur de la Guyane · GFBroad Institute · USCenter for Disease Dynamics, Economics & Policy · USHarvard University · USInstitut Pasteur · FRVirginia Tech · US

Funding

Viral Genomics: evolution, spread, and host interactionsU19AI110818 · NIAID · BROAD INSTITUTE, INC. · PI EARL, ASHLEE MIRIAM · 2014 to 2024
$66.5M
New approaches to measuring and containing the spatial spread of human pathogensR35GM124715 · NIGMS · HARVARD SCHOOL OF PUBLIC HEALTH · PI BUCKEE, CAROLINE O'FLAHERTY · 2017 to 2021
$2.0M
NIAID NIH HHS U19 AI110818NIGMS NIH HHS R35 GM124715
6 · The paper itself

Abstract

Successful infectious disease interventions can result in large reductions in parasite prevalence. Such demographic change has fitness implications for individual parasites and may shift the parasite's optimal life history strategy. Here, we explore whether declining infection rates can alter

Indexed as

Malaria, FalciparumPlasmodium falciparumAnimalsAntimalarialsGene FrequencyHumansModels, BiologicalPrevalenceAntimalarialsadaptationgenomicsmalariamodelingsexual commitment

Identifiers

PMID35867831
PMCPMC9335338
OpenAlexW4286586941

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.