Evidence map›Paper›PMID 35867761›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

The evolution of synaptic and cognitive capacity: Insights from the nervous system transcriptome of

Joshua Orvis, Caroline B Albertin, Pragya Shrestha, Shuangshuang Chen, Melanie Zheng, Cheyenne J Rodriguez, Luke J Tallon, Anup Mahurkar, Aleksey V Zimin, Michelle Kim and 5 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Molecular Physiology of the Neuronal Synapse.Current issues in molecular biology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. The role of specific isoforms of CaScientific reports · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Characterization of anFrontiers in pharmacology · 2023
    Article
  13. Article
  14. Use of an invertebrate animal model (Frontiers in neuroscience · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Joshua OrvisInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201.
Caroline B AlbertinEugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, Woods Hole, MA 02543.
Pragya ShresthaDepartment of Pharmacology, University of Maryland School of Medicine, Baltimore, MD 21201.
Shuangshuang ChenDepartment of Pharmacology, University of Maryland School of Medicine, Baltimore, MD 21201.
Melanie ZhengDepartment of Pharmacology, University of Maryland School of Medicine, Baltimore, MD 21201.
Cheyenne J RodriguezEugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, Woods Hole, MA 02543.
Luke J TallonInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201.
Anup MahurkarInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201.
Aleksey V ZiminDepartment of Biomedical Engineering, Center for Computational Biology, Johns Hopkins University, Baltimore, MD 21205.
Michelle KimCirculomics Inc., Baltimore, MD 21202.
Kelvin LiuCirculomics Inc., Baltimore, MD 21202.
Eric R KandelDepartment of Neuroscience, Columbia University, New York, NY 10032.ORCID 0000-0001-7851-6902
Claire M FraserInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201.
Wayne SossinDepartment of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.ORCID 0000-0003-1927-9315
Thomas W AbramsDepartment of Pharmacology, University of Maryland School of Medicine, Baltimore, MD 21201.
University of Maryland, Baltimore · USCirculomics (United States) · USMarine Biological Laboratory · USJohns Hopkins University · USMontreal Neurological Institute and Hospital · CANew York Psychoanalytic Society and Institute · US

Funding

NONASSOCIATIVE AND ASSOCIATIVE NEUROPLASTICITYR01MH055880 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI ABRAMS, THOMAS W · 1995 to 2015
$4.9M
CIHR 340328HHS | National Institutes of Health (NIH) R01 MH 55880Howard Hughes Medical InstituteNIMH NIH HHS R01 MH055880
6 · The paper itself

Abstract

The gastropod mollusk

Indexed as

AplysiaBiological EvolutionCognitionSynapsesAnimalsNeuronal PlasticityNeuronsProtein IsoformsProteomeTranscriptomeProtein IsoformsProteomeAplysiaevolutionneural plasticityneuromodulationsynaptic plasticity

Identifiers

PMID35867761
PMCPMC9282427
OpenAlexW4284975690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.