Evidence map›Paper›PMID 35867681›Full record

ArticlePloS one2022

Emergency department personnel patient care-related COVID-19 risk.

Nicholas M Mohr, Anusha Krishnadasan, Karisa K Harland, Patrick Ten Eyck, William R Mower, Walter A Schrading, Juan Carlos C Montoy, L Clifford McDonald, Preeta K Kutty, Elisabeth Hesse and 5 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Nicholas M MohrDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.ORCID 0000-0003-0497-5828
Anusha KrishnadasanOlive View-UCLA Education and Research Institute, Los Angeles, California, United States of America.
Karisa K HarlandDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
Patrick Ten EyckInstitute for Clinical and Translational Science, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
William R MowerDepartment of Emergency Medicine, Ronald Reagan-UCLA Medical Center, Los Angeles, California, United States of America.
Walter A SchradingDepartment of Emergency Medicine, University of Alabama and Birmingham, Birmingham, Alabama, United States of America.
Juan Carlos C MontoyDepartment of Emergency Medicine, University of California-San Francisco, San Francisco, California, United States of America.
L Clifford McDonaldDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Preeta K KuttyDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Elisabeth HesseDivision of Preparedness and Emerging Infections, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Scott SantibanezDivision of Preparedness and Emerging Infections, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
David N WeissmanRespiratory Health Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia, United States of America.
Patricia SlevARUP Laboratories, Salt Lake City, Utah, United States of America.
David A TalanDepartment of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
Project COVERED Emergency Department Network
Centers for Disease Control and Prevention · USUniversity of Iowa · USARUP Laboratories (United States) · USEducation and Research Institute · USNational Institute for Occupational Safety and Health · USRonald Reagan UCLA Medical Center · USUniversity of Alabama at Birmingham · USUniversity of California, San Francisco · US

Funding

The University of Iowa Clinical and Translational Science AwardUL1TR002537 · NCATS · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, WINOKUR, PATRICIA · 2018 to 2022
$20.0M
ACL HHS U01CK000480NCATS NIH HHS UL1 TR002537NCEZID CDC HHS U01 CK000480NCEZID CDC HHS U01 CK000643
6 · The paper itself

Abstract

objectivesEmergency department (ED) health care personnel (HCP) are at risk of exposure to SARS-CoV-2. The objective of this study was to determine the attributable risk of SARS-CoV-2 infection from providing ED care, describe personal protective equipment use, and identify modifiable ED risk factors. We hypothesized that providing ED patient care increases the probability of acquiring SARS-CoV-2 infection.

methodsWe conducted a multicenter prospective cohort study of 1,673 ED physicians, advanced practice providers (APPs), nurses, and nonclinical staff at 20 U.S. centers over 20 weeks (May to December 2020; before vaccine availability) to detect a four-percentage point increased SARS-CoV-2 incidence among HCP related to direct patient care. Participants provided monthly nasal and serology specimens and weekly exposure and procedure information. We used multivariable regression and recursive partitioning to identify risk factors.

resultsOver 29,825 person-weeks, 75 participants (4.5%) acquired SARS-CoV-2 infection (31 were asymptomatic). Physicians/APPs (aOR 1.07; 95% CI 0.56-2.03) did not have higher risk of becoming infected compared to nonclinical staff, but nurses had a marginally increased risk (aOR 1.91; 95% CI 0.99-3.68). Over 99% of participants used CDC-recommended personal protective equipment (PPE), but PPE lapses occurred in 22.1% of person-weeks and 32.1% of SARS-CoV-2-infected patient intubations. The following factors were associated with infection: household SARS-CoV-2 exposure; hospital and community SARS-CoV-2 burden; community exposure; and mask non-use in public. SARS-CoV-2 intubation was not associated with infection (attributable risk fraction 13.8%; 95% CI -2.0-38.2%), and nor were PPE lapses.

conclusionsAmong unvaccinated U.S. ED HCP during the height of the pandemic, the risk of SARS-CoV-2 infection was similar in nonclinical staff and HCP engaged in direct patient care. Many identified risk factors were related to community exposures.

Indexed as

COVID-19Emergency Service, HospitalHealth PersonnelHumansPatient CareProspective StudiesSARS-CoV-2

Identifiers

PMID35867681
PMCPMC9307202
OpenAlexW4286587768

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.