ArticlePloS one2022
Hospital length of stay among children with and without congenital anomalies across 11 European regions-A population-based data linkage study.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Survival, hospitalisation and surgery in children born with Pierre Robin sequence: a European population-based cohort study.Archives of disease in childhood · 2023Pooled it
- Article
- The Impact of Socioeconomic Inequities and Small-Area Deprivation on Child Inpatient Care: Evidence from a Quantitative Study in a Vulnerable Suburban Setting.International journal of environmental research and public health · 2026Article
- Children With Biliary Atresia Have Substantial Morbidity in Early Childhood and a High Risk of Liver Transplantation.Birth defects research · 2026Article
- Mortality amongst European children with congenital anomalies: Associations with socio-economic status in the EUROLINKCAT cohort.PloS one · 2026Observational
- Support Needs of Parents of Children With Congenital Anomalies Across Europe: A EUROlinkCAT Survey.Child: care, health and development · 2025Article
- Risk factors for hospital admission and length of stay for children with and without congenital anomalies: a EUROlinkCAT cohort study.BMJ paediatrics open · 2025Article
- The Healthcare Needs of Children With Down Syndrome in the First Year of Life: An Analysis of the EUROlinkCAT Data Linkage Study.Paediatric and perinatal epidemiology · 2025Article
- Health outcomes and drug utilisation in children with Noonan syndrome: a European cohort study.Orphanet journal of rare diseases · 2025Article
- Hospitalizations in people with down syndrome across age groups: a population-based cohort study in Switzerland.EClinicalMedicine · 2025Article
- Article
- The Association of Prenatal Diagnoses with Mortality and Long-Term Morbidity in Children with Specific Isolated Congenital Anomalies: A European Register-Based Cohort Study.Maternal and child health journal · 2024Article
- Hospital care in the first 10 years of life of children with congenital anomalies in six European countries: data from the EUROlinkCAT cohort linkage study.Archives of disease in childhood · 2024Article
- Educational outcomes of children with major congenital anomalies: Study protocol for a population-based cohort study using linked hospital and education data from England.NIHR open research · 2024Article
- Predictors of Post-Operative Hospital Length of Stay Following Complete Repair of Tetralogy of Fallot in a Pediatric Cohort in the North of England.Pediatric cardiology · 2024Article
- Timing of Cardiac Surgical Interventions and Postoperative Mortality in Children With Severe Congenital Heart Defects Across Europe: Data From the EUROlinkCAT Study.Journal of the American Heart Association · 2023Article
- Antiasthmatic prescriptions in children with and without congenital anomalies: a population-based study.BMJ open · 2023Article
- Child characteristics and health conditions associated with paediatric hospitalisations and length of stay: a population-based study.The Lancet regional health. Western Pacific · 2023Article
- Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies-A Population-Based Data Linkage Study.International journal of environmental research and public health · 2023Article
- The quality and the accuracy of codes for terminations of pregnancy for fetal anomalies recorded in hospital databases in three countries in northern Europe.Birth defects research · 2023Article
Corrections and comments
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Authors and funding
23 authors at 13 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCongenital anomalies are a leading cause of childhood morbidity, but little is known about the long-term outcomes.
objectiveTo quantify the burden of disease in childhood for children with congenital anomalies by assessing the risk of hospitalisation, the number of days spent in hospital and proportion of children with extended stays (≥10 days).
methodsEuropean population-based record-linkage study in 11 regions in eight countries including children with congenital anomalies (EUROCAT children) and without congenital anomalies (reference children) living in the same regions. The children were born between 1995 and 2014 and were followed to their tenth birthday or 31/12/2015. European meta-analyses of the outcome measures were performed by two age groups, <1 year and 1-4 years.
results99,416 EUROCAT children and 2,021,772 reference children were linked to hospital databases. Among EUROCAT children, 85% (95%-CI: 79-90%) were hospitalised in the first year and 56% (95%-CI: 51-61%) at ages 1-4 years, compared to 31% (95%-CI: 26-37%) and 25% (95%-CI: 19-31%) of the reference children. Median length of stay was 2-3 times longer for EUROCAT children in both age groups. The percentages of children with extended stays (≥10 days) in the first year were 24% (95%-CI: 20-29%) for EUROCAT children and 1% (95%-CI: 1-2%) for reference children. The median length of stay varied greatly between congenital anomaly subgroups, with children with gastrointestinal anomalies and congenital heart defects having the longest stays.
conclusionsChildren with congenital anomalies were more frequently hospitalised and median length of stay was longer. The outlook improves after the first year. Parents of children with congenital anomalies should be informed about the increased hospitalisations required for their child's care and the impact on family life and siblings, and they should be adequately supported.
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