ArticleMicrobiology spectrum2022
Early Queen Development in Honey Bees: Social Context and Queen Breeder Source Affect Gut Microbiota and Associated Metabolism.
Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Fertility Management in Pollinators: Queen Storage, Transport, and Reproductive Resilience inInsects · 2026Review
- A non-invasive method for profiling the gut microbiome and virome of honey bee queens.Scientific reports · 2026Article
- Bacterial communities of wild bee species and the western honey bee (Apis mellifera) (Hymenoptera: Apoidea): Alpine insights.Journal of insect science (Online) · 2025Article
- Honey bee (Apis mellifera) queen quality: host-microbial transcriptomes exploring the influence of age and hindgut symbiont Commensalibacter melissae.Animal microbiome · 2025Article
- Article
- Diet affects reproductive development and microbiota composition in honey bees.Animal microbiome · 2024Article
- A longitudinal study of queen health in honey bees reveals tissue specific response to seasonal changes and pathogen pressure.Scientific reports · 2024Article
- Metagenomic analysis of the honey bee queen microbiome reveals low bacterial diversity and Caudoviricetes phages.mSystems · 2024Article
- A longitudinal field study of commercial honey bees shows that non-native probiotics do not rescue antibiotic treatment, and are generally not beneficial.Scientific reports · 2024Article
- Shotgun Metagenomics Reveals Minor Micro"International journal of molecular sciences · 2024Article
- Gut microbiota-driven regulation of queen bee ovarian metabolism.Microbiology spectrum · 2023Article
- Environmental Effects on Bee Microbiota.Microbial ecology · 2023Review
- A phylogenomic and comparative genomic analysis of Commensalibacter, a versatile insect symbiont.Animal microbiome · 2023Article
- Microbiome assembly and maintenance across the lifespan of bumble bee workers.Molecular ecology · 2023Article
- A high-throughput sequencing survey characterizing European foulbrood disease and Varroosis in honey bees.Scientific reports · 2023Article
- Developing Strategies to Help Bee Colony Resilience in Changing Environments.Animals : an open access journal from MDPI · 2022Review
- Micro"bee"ota: Honey Bee Normal Microbiota as a Part of Superorganism.Microorganisms · 2022Review
- Changes in gut microbiota and metabolism associated with phenotypic plasticity in the honey beeFrontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The highly social honey bee has dense populations but a significantly reduced repertoire of immune genes relative to solitary species, suggesting a greater reliance on social immunity. Here we investigate immune gene expression and gut microbial succession in queens during colony introduction. Recently mated queens were placed into an active colony or a storage hive for multiple queens: a queen-bank. Feeding intensity, social context, and metabolic demand differ greatly between the two environments. After 3 weeks, we examined gene expression associated with oxidative stress and immunity and performed high-throughput sequencing of the queen gut microbiome across four alimentary tract niches. Microbiota and gene expression in the queen hindgut differed by time, queen breeder source, and metabolic environment. In the ileum, upregulation of most immune and oxidative stress genes occurred regardless of treatment conditions, suggesting postmating effects on gut gene expression. Counterintuitively, queens exposed to the more social colony environment contained significantly less bacterial diversity indicative of social immune factors shaping the queens microbiome. Queen bank queens resembled much older queens with decreased Alpha 2.1, greater abundance of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.