Evidence map›Paper›PMID 35866887›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2022

Profiling the NOTCH2NLC GGC Repeat Expansion in Parkinson's Disease in the European Population.

Kimberley J Billingsley, Pilar Alvarez Jerez, Francis P Grenn, Sara Bandres-Ciga, Laksh Malik, Dena Hernandez, Ali Torkamani, Mina Ryten, John Hardy, United Kingdom Brain Expression Consortium (UKBEC) and 12 more

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 8 institutions in 3 countries.

Kimberley J BillingsleyLaboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.ORCID 0000-0002-8003-4029
Pilar Alvarez JerezLaboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Francis P GrennLaboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Sara Bandres-CigaLaboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.ORCID 0000-0003-0056-1361
Laksh MalikCenter for Alzheimer's and Related Dementias, National Institute on Aging, Bethesda, Maryland, USA.
Dena HernandezLaboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Ali TorkamaniThe Scripps Research Institute, La Jolla, California, USA.ORCID 0000-0003-0232-8053
Mina RytenNIHR Great Ormond Street Hospital Biomedical Research Centre, University College London, London, United Kingdom.
John HardyUK Dementia Research Institute and Department of Neurodegenerative Disease and Reta Lila Weston Institute, UCL Queen Square Institute of Neurology and UCL Movement Disorders Centre, University College London, London, United Kingdom.
United Kingdom Brain Expression Consortium (UKBEC)
Sonja W ScholzNeurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA.ORCID 0000-0002-6623-0429
Bryan J TraynorLaboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Clifton L DalgardDepartment of Anatomy Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Debra J EhrlichParkinson's Disease Clinic, Office of the Clinical Director, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA.
Toshiko TanakaTranslational Gerontology Branch, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Luigi FerrucciTranslational Gerontology Branch, National Institute on Aging, NIH, Baltimore, Maryland, USA.
Thomas G BeachParkinson's Disease Clinic, Office of the Clinical Director, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA.
Geidy E SerranoCivin Laboratory for Neuropathology, Banner Sun Health Research Institute, Sun City, Arizona, USA.
Jinhui DingLaboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
J Raphael GibbsLaboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Cornelis BlauwendraatLaboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Andrew B SingletonLaboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
National Institute on Aging · USJohns Hopkins University · USNational Institute of Neurological Disorders and Stroke · USBanner Sun Health Research Institute · USGreat Ormond Street Hospital · GBHong Kong University of Science and Technology · HKScripps Research Institute · USUniformed Services University of the Health Sciences · US

Funding

Research Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI REIMAN, ERIC MICHAEL · 2001 to 2020
$32.5M
Scripps Translational Science InstituteUL1TR002550 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2018 to 2022
$28.9M
Genetic characterization of atypical parkinsonismZIANS003154 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI SCHOLZ, SONJA · 2016 to 2025
$15.4M
National Brain and Tissue Resource for Parkinson's Disease and Related DisordersU24NS072026 · NINDS · BANNER SUN HEALTH RESEARCH INSTITUTE · PI BEACH, THOMAS G · 2011 to 2015
$7.8M
Genome wide SNP analysis in Parkinson's diseaseZ01AG000949 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW B · 2006 to 2008
$2.6M
Intramural NIH HHS Z01 AG000949Intramural NIH HHS Z99 AG999999Intramural NIH HHS ZIA NS003154Medical Research Council G0701075Medical Research Council G0901254Medical Research Council MR/N008324/1Medical Research Council MR/N026004/1NCATS NIH HHS UL1 TR002550NIA NIH HHS P30 AG019610NINDS NIH HHS U24 NS072026
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Parkinson DiseaseHumansIntranuclear Inclusion BodiesTrinucleotide Repeat Expansion

Identifiers

PMID35866887
PMCPMC12159426
OpenAlexW4286560311

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.