Evidence map›Paper›PMID 35866606›Full record

ArticleActa biochimica et biophysica Sinica2022

miR-335-5p regulates the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection by directly regulating SP1.

Runwei Ma, Dayong Zhang, Yi Song, Jichang Kong, Chunjie Mu, Pin Shen, Wenting Gui

Open access · diamondAbstract read
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Targeting Arterial Dysfunction in Cardiovascular Disease Using Stem Cell-Based Therapies.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Runwei MaDepartment of Cardiovascular Surgery, Fuwai Yunnan Cardiovascular Hospital, Kunming 650102, China.
Dayong ZhangDepartment of Cardiovascular Surgery, Guangyuan Central Hospital, Guangyuan 628099, China.
Yi SongDepartment of Extracorporeal Circulation, Fuwai Yunnan Cardiovascular Hospital, Kunming 650102, China.
Jichang KongDepartment of Cardiovascular Surgery, Fuwai Yunnan Cardiovascular Hospital, Kunming 650102, China.
Chunjie MuDepartment of Cardiovascular Surgery, Fuwai Yunnan Cardiovascular Hospital, Kunming 650102, China.
Pin ShenDepartment of Cardiovascular Surgery, Fuwai Yunnan Cardiovascular Hospital, Kunming 650102, China.
Wenting GuiDepartment of Extracorporeal Circulation, Fuwai Yunnan Cardiovascular Hospital, Kunming 650102, China.
Fuwai Yunnan Cardiovascular Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uncontrolled proliferation, migration and phenotypic switching of vascular smooth muscle cells (VSMCs) are important steps in the development and progression of aortic dissection (AD). The function and potential mechanism of miR-335-5p in the pathogenesis of AD are explored in this study. Specifically, the biological function of miR-335-5p is explored

Indexed as

Aortic DissectionMicroRNAsMyocytes, Smooth MuscleSp1 Transcription FactorAngiotensin IIBecaplerminCell MovementCell ProliferationCells, CulturedHumansLuciferasesMuscle, Smooth, VascularPhenotypeAngiotensin IIBecaplerminLuciferasesMicroRNAsMIRN335 microRNA, humanSP1 protein, humanSp1 Transcription Factoraortic dissectionmiR-335-5pphenotypic switchvascular smooth muscle cells

Identifiers

PMID35866606
PMCPMC9828317
OpenAlexW4283466757

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.