Evidence map›Paper›PMID 35866372›Full record

ArticleThe FEBS journal2023

Hydrogen peroxide induces heme degradation and protein aggregation in human neuroglobin: roles of the disulfide bridge and hydrogen-bonding in the distal heme cavity.

Giulia Di Rocco, Fabrizio Bernini, Gianantonio Battistuzzi, Antonio Ranieri, Carlo Augusto Bortolotti, Marco Borsari, Marco Sola

Open access · hybridAbstract read
In one paragraph

Article in The FEBS journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Engineering an indoleamine 2,3-dioxygenase immunotherapyMolecular systems design & engineering · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giulia Di RoccoDepartment of Life Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0000-0002-3187-2210
Fabrizio BerniniDepartment of Chemical and Geological Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0000-0002-2598-7716
Gianantonio BattistuzziDepartment of Chemical and Geological Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0000-0003-4716-5745
Antonio RanieriDepartment of Life Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0000-0001-6686-669X
Carlo Augusto BortolottiDepartment of Life Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0000-0002-5701-5727
Marco BorsariDepartment of Chemical and Geological Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0000-0002-3612-4764
Marco SolaDepartment of Chemical and Geological Sciences, University of Modena and Reggio Emilia, Italy.ORCID 0000-0002-2700-4154
University of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, human neuroglobin (hNgb) was found to undergo H

Indexed as

Hydrogen PeroxideProtein AggregatesDisulfidesGlobinsHemeHumansHydrogenNerve Tissue ProteinsNeuroglobinDisulfidesGlobinsHemeHydrogenHydrogen PeroxideNerve Tissue ProteinsNeuroglobinProtein Aggregatesaggregationamyloidelectronic and MCD spectroscopiesfibrilhydrogen peroxideneuroglobin

Identifiers

PMID35866372
PMCPMC10087938
OpenAlexW4286717525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.