Evidence map›Paper›PMID 35865562›Full record

ArticleRSC advances2022

Coupling of acceptor-substituted diazo compounds and tertiary thioamides: synthesis of enamino carbonyl compounds and their pharmacological evaluation.

Jim Secka, Arpan Pal, Francis A Acquah, Blaine H M Mooers, Anand B Karki, Dania Mahjoub, Mohamed K Fakhr, David R Wallace, Takuya Okada, Naoki Toyooka and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Jim SeckaDepartment of Chemistry and Biochemistry, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA syed-hussaini@utulsa.edu.
Arpan PalDepartment of Chemistry and Biochemistry, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA syed-hussaini@utulsa.edu.
Francis A AcquahDepartment of Biochemistry and Molecular Biology, University of Oklahoma of Health Sciences Center Oklahoma City OK 73104 Unites States.ORCID https://orcid.org/0000-0002-4534-9156
Blaine H M MooersDepartment of Biochemistry and Molecular Biology, University of Oklahoma of Health Sciences Center Oklahoma City OK 73104 Unites States.ORCID https://orcid.org/0000-0001-8181-8987
Anand B KarkiDepartment of Biological Science, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA.
Dania MahjoubDepartment of Biological Science, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA.
Mohamed K FakhrDepartment of Biological Science, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA.
David R WallaceDepartment of Pharmacology and Physiology, Oklahoma State University Center for Health Sciences Tulsa Oklahoma 74107 USA.
Takuya OkadaFaculty of Engineering, University of Toyama 3190 Gofuku Toyama 930-8555 Japan.
Naoki ToyookaFaculty of Engineering, University of Toyama 3190 Gofuku Toyama 930-8555 Japan.
Adama KutaDepartment of Chemistry and Biochemistry, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA syed-hussaini@utulsa.edu.
Naga KoduriDepartment of Chemistry and Biochemistry, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA syed-hussaini@utulsa.edu.
Deacon HerndonDepartment of Chemistry and Biochemistry, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA syed-hussaini@utulsa.edu.
Kenneth P RobertsDepartment of Chemistry and Biochemistry, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA syed-hussaini@utulsa.edu.
Zhiguo WangDepartment of Chemistry and Biochemistry, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA syed-hussaini@utulsa.edu.
Bethany HilemanDepartment of Chemistry and Biochemistry, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA syed-hussaini@utulsa.edu.
Nisha RajagopalDepartment of Chemistry and Biochemistry, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA syed-hussaini@utulsa.edu.
Syed R HussainiDepartment of Chemistry and Biochemistry, The University of Tulsa 800 S. Tucker Drive Tulsa Oklahoma 74104 USA syed-hussaini@utulsa.edu.ORCID https://orcid.org/0000-0002-5425-3332
University of Tulsa · USUniversity of Oklahoma Health Sciences Center · USUniversity of Toyama · JPOklahoma State University Center for Health Sciences · US

Funding

Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ROBERT S. MANNEL · 2018 to 2026
$27.1M
Structure-Function Studies of MsvR, a Methanogen-Specific Transcriptional RegulaP20GM103640 · NIGMS · UNIVERSITY OF OKLAHOMA · PI THOMAS, LEONARD M · 2012 to 2021
$20.4M
Blocking tumor progression in therapy-responsive RET aberration-associated cancerR01CA242845 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI AHNERT, JORDI RODON, MOOERS, BLAINE H. M. · 2020 to 2024
$1.9M
NCI NIH HHS P30 CA225520NCI NIH HHS R01 CA242845NIGMS NIH HHS P20 GM103640
6 · The paper itself

Abstract

This paper describes the synthesis of enamino carbonyl compounds by the copper(i)-catalyzed coupling of acceptor-substituted diazo compounds and tertiary thioamides. We plan to use this method to synthesize indolizidine (-)-237D analogs to find α6-selective antismoking agents. Therefore, we also performed

Identifiers

PMID35865562
PMCPMC9256013
OpenAlexW4285186744

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.