Evidence map›Paper›PMID 35865521›Full record

ArticleFrontiers in immunology2022

Positron Emission Tomography to Improve Assessment of Interstitial Lung Disease in Patients With Systemic Sclerosis Eligible for Autologous Stem Cell Transplantation.

Bo Broens, Conny J van der Laken, Gerben J C Zwezerijnen, Esther J Nossent, Lilian J Meijboom, Julia Spierings, Jeska K de Vries-Bouwstra, Jacob M van Laar, Alexandre E Voskuyl

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Bo BroensDepartment of Rheumatology and Clinical Immunology, Amsterdam UMC, Amsterdam, Netherlands.
Conny J van der LakenDepartment of Rheumatology and Clinical Immunology, Amsterdam UMC, Amsterdam, Netherlands.
Gerben J C ZwezerijnenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Esther J NossentDepartment of Pulmonary Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Lilian J MeijboomDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands.
Julia SpieringsDepartment of Rheumatology and Clinical Immunology, University Medical Centre Utrecht, Utrecht, Netherlands.
Jeska K de Vries-BouwstraDepartment of Rheumatology, Leiden University Medical Center, Leiden, Netherlands.
Jacob M van LaarDepartment of Rheumatology and Clinical Immunology, University Medical Centre Utrecht, Utrecht, Netherlands.
Alexandre E VoskuylDepartment of Rheumatology and Clinical Immunology, Amsterdam UMC, Amsterdam, Netherlands.
Amsterdam University Medical Centers · NLUniversity Medical Center Utrecht · NLUniversity of Amsterdam · NLLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Positron emission tomography (PET) is a promising technique to improve the assessment of systemic sclerosis associated interstitial lung disease (SSc-ILD). This technique could be of particular value in patients with severe diffuse cutaneous SSc (dcSSc) that are possibly eligible for autologous hematopoietic stem cell transplantation (aHSCT). aHSCT is a potentially effective therapy for patients with severe dcSSc and ILD, leading to stabilization or improvement of lung function. However, there is a high need to improve patient selection, which includes (1) the selection of patients with rapidly progressive ILD for early rather than last-resort aHSCT (2) the prediction of treatment response on ILD and (3) the understanding of the mechanism(s) of action of aHSCT in the lungs. As previous studies with

Indexed as

Hematopoietic Stem Cell TransplantationLung Diseases, InterstitialScleroderma, SystemicHumansPositron-Emission TomographyTransplantation, Autologousinterstitial lung diseaselung fibrosispositron emission tomographysclerodermastem cell transplantationsystemic sclerosis

Identifiers

PMID35865521
PMCPMC9294594
OpenAlexW4283808298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.