Evidence map›Paper›PMID 35865321›Full record

ArticleSaudi journal of biological sciences2022

Ameliorative effect of L-carnitine on lambda-cyhalothrin-induced anatomical and reproductive aberrations in albino mice.

Nawal M Al Malahi, Masaa M Al Jumaily, Elham A S Al-Shaibani, Reem A Alajmi, Afrah F Alkhuriji, Jameel Al-Tamimi, Ahmad R Alhimaidi

Open access · hybridAbstract read
In one paragraph

Article in Saudi journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Nawal M Al MalahiZoology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Masaa M Al JumailyBiological Science Department, College of Science, Sana'a University, Sana'a, Yemen.
Elham A S Al-ShaibaniBiological Science Department, College of Science, Sana'a University, Sana'a, Yemen.
Reem A AlajmiZoology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Afrah F AlkhurijiZoology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Jameel Al-TamimiZoology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Ahmad R AlhimaidiZoology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
King Saud University · SASana'a University · YE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this research was to look at how the pesticide lambda-cyhalothrin (LCT) affected the liver, kidney, testis, and ovary of albino mice; and on morphological and skeletal features of the newborn of treated females. The study also aimed to test the ameliorative effects of L-carnitine (LC) against (LCT). Five sets of mice were created, Group 1 acted as the control, while Group 2 received a high dose of LCT, Group 3 received a high dose of LCT + LC, Group 4 received a low dose of LCT that was a residue of in khat (Qat), and Group 5 received a low dose of LCT + LC. The findings revealed that the treated groups' body weights were reduced significantly, whereas the absolute and relative weights of the liver in all groups were statistically decreased insignificantly. There were histopathological changes in the tissues in groups 2 and 4. While the tissues of the ovary and testis showed recovery in groups 3 and 5. When compared to the control group, the values of the seminiferous tubules parameters were statistically significant in the 3 and 5 groups. The newborn had a high dose of pesticides and showed some malformations in the skeleton. However, in group 3 the skeletal malformation was minimized and in-group 5 the skeleton malformations had completely disappeared. It could be concluded that LCT is highly harmful to mouse tissues and caused neonatal malformations, whereas LC has a marked protective effect against LCT.

Indexed as

Antioxidant L-carnitineInsecticidesKhatMice histological studyPyrethroid Lambda-cyhalothrin

Identifiers

PMID35865321
PMCPMC9293953
OpenAlexW4283792035

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.