Evidence map›Paper›PMID 35865221›Full record

ArticleWellcome open research2022

Targeted protein degradation using deGradFP in

Midori Ishii, Bungo Akiyoshi

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Targeted protein degradation might present a novel therapeutic approach in the fight against African trypanosomiasis.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2023
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Midori IshiiDepartment of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.ORCID https://orcid.org/0000-0001-9597-9458
Bungo AkiyoshiDepartment of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.ORCID https://orcid.org/0000-0001-6010-394X
University of Oxford · GB

Funding

Wellcome Trust 210622
6 · The paper itself

Abstract

Targeted protein degradation is an invaluable tool in studying the function of proteins. Such a tool was not available in

Indexed as

deGradFPdegronkinetochorekinetoplastidtargeted protein degradationTrypanosoma brucei

Identifiers

PMID35865221
PMCPMC9277568.2
OpenAlexW4283320259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.