Evidence map›Paper›PMID 35865201›Full record

ArticleRSC advances2022

Gold nanoparticles decorated with ovalbumin-derived epitopes: effect of shape and size on T-cell immune responses.

Elena A Egorova, Gerda E M Lamers, Fazel Abdolahpur Monikh, Aimee L Boyle, Bram Slütter, Alexander Kros

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elena A EgorovaDepartment of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University The Netherlands a.kros@chem.leidenuniv.nl.ORCID https://orcid.org/0000-0003-4548-5104
Gerda E M LamersCore Facility Microscopy, Institute of Biology, Leiden University The Netherlands.
Fazel Abdolahpur MonikhEnvironmental Biology, Institute of Environmental Sciences, Leiden University The Netherlands.ORCID https://orcid.org/0000-0001-9500-5303
Aimee L BoyleMacromolecular Biochemistry, Leiden Institute of Chemistry, Leiden University The Netherlands.ORCID https://orcid.org/0000-0003-4176-6080
Bram SlütterLeiden Academic Centre for Drug Research, Biotherapeutics, Leiden University The Netherlands.ORCID https://orcid.org/0000-0003-3996-0503
Alexander KrosDepartment of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University The Netherlands a.kros@chem.leidenuniv.nl.ORCID https://orcid.org/0000-0002-3983-3048
Leiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold nanoparticles (GNPs) can be manufactured in various shapes, and their size is programmable, which permits the study of the effects imposed by these parameters on biological processes. However, there is currently no clear evidence that a certain shape or size is beneficial. To address this issue, we have utilised GNPs and gold nanorods (GNRs) functionalised with model epitopes derived from chicken ovalbumin (OVA

Identifiers

PMID35865201
PMCPMC9260517
OpenAlexW4285200567

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.