Evidence map›Paper›PMID 35865023›Full record

ReviewCJC open2022

The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women - Chapter 6: Sex- and Gender-Specific Diagnosis and Treatment.

Monica Parry, Harriette G C Van Spall, Kerri-Anne Mullen, Sharon L Mulvagh, Christine Pacheco, Tracey J F Colella, Marie-Annick Clavel, Shahin Jaffer, Heather J A Foulds, Jasmine Grewal and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in CJC open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Stable angina in young women.European heart journal · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Sex-Related Differences in Heart Failure Diagnosis.Current heart failure reports · 2023
    Review
  12. [Gender-specific differences in cardiology].Innere Medizin (Heidelberg, Germany) · 2023
    Review
  13. It's NotJournal of the American Heart Association · 2023
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 13 institutions in 2 countries.

Monica ParryLawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Harriette G C Van SpallDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Kerri-Anne MullenDivision of Cardiac Prevention and Rehabilitation, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Sharon L MulvaghDivision of Cardiology, Dalhousie University, Halifax, Nova Scotia, Canada.
Christine PachecoHôpital Pierre-Boucher, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada.
Tracey J F ColellaLawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Marie-Annick ClavelInstitut Universitaire de Cardiologie et de pneumologie de Québec- Université Laval, Quebec City, Quebec, Canada.
Shahin JafferDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Heather J A FouldsCollege of Kinesiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Jasmine GrewalDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Marsha HardyCanadian Women's Heart Health Alliance, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Jennifer A D PriceWomen's College Hospital, Toronto, Ontario, Canada.
Anna L E LevinssonMontreal Heart Institute, Montreal, Quebec, Canada.
Christine A GonsalvesSchool of Human Kinetics, Laurentian University, Sudbury, Ontario, Canada.
Colleen M NorrisFaculty of Nursing, University of Alberta, Edmonton, Alberta, Canada.
University of British Columbia · CAUniversity of Ottawa · CACentre Hospitalier de l’Université de Montréal · CADalhousie University · CAImpact · CAInstitut universitaire de cardiologie et de pneumologie de Québec · CALaurentian University · CAMontreal Heart Institute · CAUniversity Health Network · CAUniversity of Alberta · CAUniversity of Saskatchewan · CAUniversity of Toronto · CAWomen's College Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This chapter summarizes the sex- and gender-specific diagnosis and treatment of acute/unstable presentations and nacute/stable presentations of cardiovascular disease in women. Guidelines, scientific statements, systematic reviews/meta-analyses, and primary research studies related to diagnosis and treatment of coronary artery disease, cerebrovascular disease (stroke), valvular heart disease, and heart failure in women were reviewed. The evidence is summarized as a narrative, and when available, sex- and gender-specific practice and research recommendations are provided. Acute coronary syndrome presentations and emergency department delays are different in women than they are in men. Coronary angiography remains the gold-standard test for diagnosis of obstructive coronary artery disease. Other diagnostic imaging modalities for ischemic heart disease detection (eg, positron emission tomography, echocardiography, single-photon emission computed tomography, cardiovascular magnetic resonance, coronary computed tomography angiography) have been shown to be useful in women, with their selection dependent upon both the goal of the individualized assessment and the testing resources available. Noncontrast computed tomography and computed tomography angiography are used to diagnose stroke in women. Although sex-specific differences appear to exist in the efficacy of standard treatments for diverse presentations of acute coronary syndrome, many cardiovascular drugs and interventions tested in clinical trials were not powered to detect sex-specific differences, and knowledge gaps remain. Similarly, although knowledge is evolving about sex-specific difference in the management of valvular heart disease, and heart failure with both reduced and preserved ejection fraction, current guidelines are lacking in sex-specific recommendations, and more research is needed.

Identifiers

PMID35865023
PMCPMC9294990
OpenAlexW4224227025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.