Evidence map›Paper›PMID 35865000›Full record

ArticleDrugs in context2022

The role of hypochlorous acid in the management of eye infections: a case series.

Chiara Bertone, Antonella Mollicone, Stefano Russo, Paola Sasso, Romina Fasciani, Cinzia Riccardi, Mirella Lizzano, ALI working group (listed in the appendix)

Open access · goldAbstract readCase Reports
In one paragraph

Article in Drugs in context, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Commercially available antiseptics show highFrontiers in veterinary science · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chiara BertoneFoundation IRCCS Polyclinic San Matteo, Pavia, Italy.
Antonella MolliconePrivate Practice, Studio Medico Ippocrate, Rome, Italy.
Stefano RussoVilla dei Fiori Hospital, Acerra, Naples, Italy.
Paola SassoInstitute of Ophthalmology, University Polyclinic Foundation Agostino Gemelli - IRCCS, Rome, Italy.
Romina FascianiInstitute of Ophthalmology, University Polyclinic Foundation Agostino Gemelli - IRCCS, Rome, Italy.
Cinzia RiccardiFabrizio Spaziani Hospital, Frosinone, Italy.
Mirella LizzanoPrivate Practice, Milan, Italy.
ALI working group (listed in the appendix)
Agostino Gemelli University Polyclinic · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITVilla Torri Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experiences from clinical practice suggest that hypochlorous acid (HOCl) used as adjuvant treatment can shorten the time to clinical resolution of blepharitis, particularly in relation to the ophthalmic complications that often occur with a blepharitis diagnosis. In addition, in clinical practice, HOCl adjuvant treatment also resulted in a viable option for the management of ophthalmic disorders other than blepharitis. This case series presents and discusses real-life experiences with using an HOCl ophthalmic spray to manage eye infections, further characterizing the use of HOCl for ophthalmic applications.

Indexed as

blepharitiscase seriesherpes zosterHOClhypochlorous acidinflammationocular infections

Identifiers

PMID35865000
PMCPMC9267159
OpenAlexW4283735658

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.