Evidence map›Paper›PMID 35864993›Full record

ArticleInternational journal of general medicine2022

Impact of Geographical Location on the Gut Microbiota Profile in Egyptian Children with Type 1 Diabetes Mellitus: A Pilot Study.

Nahla M Elsherbiny, Mohammed Ramadan, Nagla H Abu Faddan, Elham Ahmed Hassan, Mohamed E Ali, Abeer Sharaf El-Din Abd El-Rehim, Wael A Abbas, Mohamed A A Abozaid, Ebtisam Hassanin, Ghada A Mohamed and 2 more

Abstract read
In one paragraph

Article in International journal of general medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nahla M ElsherbinyDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut, Egypt.ORCID 0000-0002-5431-6583
Mohammed RamadanDepartment of Microbiology and Immunology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, Egypt.
Nagla H Abu FaddanDepartment of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.
Elham Ahmed HassanDepartment of Gastroenterology and Tropical Medicine, Faculty of Medicine, Assiut University, Assiut, Egypt.ORCID 0000-0003-2575-758X
Mohamed E AliDepartment of Microbiology and Immunology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, Egypt.
Abeer Sharaf El-Din Abd El-RehimDepartment of Gastroenterology and Tropical Medicine, Faculty of Medicine, Assiut University, Assiut, Egypt.ORCID 0000-0002-7549-3394
Wael A AbbasDepartment of Internal Medicine, Gastroenterology and Hepatology Unit, Faculty of Medicine, Assiut University, Assiut, Egypt.ORCID 0000-0001-5554-8207
Mohamed A A AbozaidDepartment of Internal Medicine, Gastroenterology and Hepatology Unit, Faculty of Medicine, Assiut University, Assiut, Egypt.
Ebtisam HassaninClinical Pathology, Ministry of Health, Assiut, Egypt.
Ghada A MohamedDepartment of Internal Medicine, Endocrine Unit, Faculty of Medicine, Assiut University, Assiut, Egypt.
Helal F HettaDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut, Egypt.ORCID 0000-0001-8541-7304
Mohammed SalahDepartment of Microbiology and Immunology, Faculty of pharmacy, Port Said University, Port Said, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the compositional and functional characteristics of T1DM-associated gut microbiota in two Egyptian cities and to study the geographical locality effects. Patients and Methods: This case-control study included 32 children with controlled T1DM and 16 controls, selected from two different regions of Egypt. The gut microbiota of both diabetic and control children was analyzed through 16S rRNA gene sequencing; this was done using the Illumina MiSeq platform. Results: Consistent findings among the diabetic children included significantly lower alpha diversity than the control children, as well as a lower mean Conclusion: There are a number of consistent changes in the microbiota profile characterizing the diabetic groups irrespective of the geographical location including significantly lower alpha diversity, mean

Indexed as

childrendysbiosisgut microbiotatype 1 diabetes mellitus

Identifiers

PMID35864993
PMCPMC9296103

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.