An 80-year-old woman with myelofibrosis and diffuse mosaic attenuation on chest computed tomography.

Harpreet Singh, Jonathan S Kurman, Chinmay T Jani, Nagarjun Rao, Bryan S Benn

Open access · goldAbstract readCase Reports

In one paragraph

Article in Respiratory medicine case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.3field-weighted citation impact, top 41% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Harpreet SinghDepartment of Medicine, Division of Pulmonary and Critical Care, Medical College of, Wisconsin, Milwaukee, WI, USA.

Jonathan S KurmanDepartment of Medicine, Division of Pulmonary and Critical Care, Medical College of, Wisconsin, Milwaukee, WI, USA.

Chinmay T JaniDepartment of Medicine, Mount Auburn Hospital/Beth Israel Lahey Health, Cambridge, MA, USA.

Nagarjun RaoDepartment of Pathology, Aurora Clinical Laboratories/Great Lakes Pathologists, Aurora West Allis Medical Center, West Allis, WI, USA.

Bryan S BennDepartment of Medicine, Division of Pulmonary and Critical Care, Medical College of, Wisconsin, Milwaukee, WI, USA.

Medical College of Wisconsin · USAurora West Allis Medical Center · USMount Auburn Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 80-year-old woman with myelofibrosis sought evaluation for progressive dyspnea. Her past medical history included essential thrombocytosis, which transformed to myelofibrosis. Inspiratory computed tomography of chest showed diffuse mosaic attenuation with lymphadenopathy. Flexible bronchoscopy with lymph node and pulmonary parenchymal cryo biopsy revealed nodular deposits of extramedullary hematopoiesis in lung parenchyma and moderate to severe vascular medial and intimal thickening of pulmonary vasculature consistent with pulmonary parenchymal extramedullary hematopoiesis associated with pulmonary hypertension (a rare compensatory mechanism in myeloproliferative disorders). In this report, we explore the manifestations, pathogenesis, treatment, and prognosis of pulmonary extramedullary hematopoiesis reported in the literature.

Indexed as

BAL, bronchoalveolar lavageCT, computed tomographyDLCO, diffusion capacity of lung for carbon monoxideEBUS, endobronchial ultrasoundEMH, extramedullary hematopoiesisExtramedullary hematopoiesisFEV1, forced expiratory volume in 1FNAB, fine-needle aspiration biopsyFVC, forced vital capacityLPM, liters per minuteMosaic attenuationMPO, myeloperoxidaseMyelofibrosisNSIP, nonspecific interstitial pneumoniaPEMH, pulmonary extramedullary hematopoiesisPFT, Pulmonary function testingPH, pulmonary hypertensionRES, reticuloendothelial systemTBLC, transbronchial lung cryobiopsyTBNA, transbronchial needle aspirationTLC, total lung capacity

Identifiers

PMID35864977

DOI10.1016/j.rmcr.2022.101705

PMCPMC9293942

OpenAlexW4285010953

What OpenQuestion holds

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.