Evidence map›Paper›PMID 35864965›Full record

ReviewInternational journal of biological sciences2022

The Role of DACT Family Members in Tumorigenesis and Tumor Progression.

Yu Zeng, Jiqin Zhang, Jianhe Yue, Guoqiang Han, Weijia Liu, Lin Liu, Xin Lin, Yan Zha, Jian Liu, Ying Tan

Open access · goldAbstract readReview
In one paragraph

Review in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yu ZengDepartment of Neurosurgery, Guizhou Provincial People's Hospital, Guiyang, China.
Jiqin ZhangDepartment of Anesthesiology, Guizhou Provincial People's Hospital, Guiyang, China.
Jianhe YueDepartment of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Guoqiang HanDepartment of Neurosurgery, Guizhou Provincial People's Hospital, Guiyang, China.
Weijia LiuDepartment of Respiratory and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, China.
Lin LiuDepartment of Respiratory and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, China.
Xin LinDepartment of Nephrology, Guizhou Provincial People's Hospital, Guiyang, China.
Yan ZhaDepartment of Nephrology, Guizhou Provincial People's Hospital, Guiyang, China.
Jian LiuDepartment of Neurosurgery, Guizhou Provincial People's Hospital, Guiyang, China.
Ying TanDepartment of Neurosurgery, Guizhou Provincial People's Hospital, Guiyang, China.
Guizhou Provincial People's Hospital · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disheveled-associated antagonist of β-catenin (DACT), which ubiquitously expressed in human tissue, is critical for regulating cell proliferation and several developmental processes in different cellular contexts. In addition, DACT is essential for some other cellular processes, such as cell apoptosis, migration and differentiation. Given the importance of DACT in these cellular processes, many scientists are gradually interested in studying the role of DACT in tumorigenesis and cancer progression. This review article focuses on the latest research regarding the essential functions and potential DACT mechanisms in the occurrence and progression of tumors. Our study indicates that DACT may act as a tumor biomarker for cancer diagnosis and prognosis, as well as a promising therapeutic target in cancers.

Indexed as

Biomarkers, TumorCarcinogenesisCell DifferentiationCell ProliferationHumansBiomarkers, TumorApoptosisCancerDACT family membersInvasionPrognosisProliferation

Identifiers

PMID35864965
PMCPMC9295065
OpenAlexW4285817678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.