Evidence map›Paper›PMID 35864912›Full record

ArticlePulmonary circulation2022

Caveolin-1 associated with severe (pediatric-onset) presentation of pulmonary arterial hypertension.

Rachel Farrell, Elizabeth Colglazier, Claire Parker, Leah Stevens, Eric D Austin, Jeffrey R Fineman

Open access · goldAbstract readCase Reports
In one paragraph

Article in Pulmonary circulation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rachel FarrellDepartment of Pediatrics UCSF Benioff Children's Hospital San Francisco California USA.
Elizabeth ColglazierDepartment of Pediatrics UCSF Benioff Children's Hospital San Francisco California USA.
Claire ParkerDepartment of Pediatrics UCSF Benioff Children's Hospital San Francisco California USA.
Leah StevensDepartment of Pediatrics UCSF Benioff Children's Hospital San Francisco California USA.
Eric D AustinDepartment of Pediatrics Vanderbilt University Medical Center Nashville Tennessee USA.
Jeffrey R FinemanDepartment of Pediatrics UCSF Benioff Children's Hospital San Francisco California USA.ORCID 0000-0001-9740-405X
UCSF Benioff Children's Hospital · USVanderbilt University Medical Center · US

Funding

TGF-ß-SOX18-Collagen metabolism in pulmonary vascular disease associated with CHDP01HL146369 · NHLBI · UNIVERSITY OF ARIZONA · PI Stephen M Black · 2020 to 2026
$18.7M
NHLBI NIH HHS P01 HL146369
6 · The paper itself

Abstract

There has been a growing interest in the role that genetic factors influence pediatric pulmonary vascular disease. In fact, data suggests that genetic factors contribute to ~42% of pediatric-onset pulmonary hypertension. Although animal and human studies suggest that aberrations in Caveolin1 (

Indexed as

CAV1pulmonary hypertensionpulmonary vascular disease

Identifiers

PMID35864912
PMCPMC9294289
OpenAlexW4283030007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.