Evidence map›Paper›PMID 35864896›Full record

ArticleFrontiers in physiology2022

Effects of Mexiletine on a Race-specific Mutation in Na

Xin Wu, Yawei Li, Liang Hong

Abstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Hv1 channel in immune cells and pharmacology.Pharmacological research · 2025
    Review
  5. Ion channel mutations and cancer.Biochemistry and biophysics reports · 2025
    Review
  6. A novel gain-of-function mutationAmerican journal of cardiovascular disease · 2025
    Article
  7. Ion Channels in the Immune Response of Asthma.Journal of respiratory biology and translational medicine · 2024
    Article
  8. The Antidepressant Paroxetine Reduces the Cardiac Sodium Current.International journal of molecular sciences · 2023
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xin WuDepartment of Medicine, University of Illinois at Chicago, Chicago, IL, United States.
Yawei LiDepartment of Preventive Medicine, Northwestern University, Chicago, IL, United States.
Liang HongDepartment of Medicine, University of Illinois at Chicago, Chicago, IL, United States.

Funding

Regulation of Voltage-gated Proton ChannelR01GM139991 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI HONG, LIANG · 2021 to 2025
$1.6M
NIGMS NIH HHS R01 GM139991
6 · The paper itself

Abstract

The voltage-gated sodium channel Na

Indexed as

electrophysiologyLQT syndromeNav1.5patch clampvoltage-gated sodium channel

Identifiers

PMID35864896
PMCPMC9294368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.