ArticleBMC infectious diseases2022
Prognostic value of platelet count-related ratios on admission in patients with pyogenic liver abscess.
Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Association between C-reactive protein-to-platelet ratio and acute kidney injury in cardiac arrest survivors.BMC cardiovascular disorders · 2026Article
- A Risk Model Incorporating the Novel Inflammatory Biomarker CD64 for Predicting Bloodstream Infection in Suspected Cases.Antibiotics (Basel, Switzerland) · 2026Article
- Predictive Value of Platelet-Based Indexes for Mortality in Sepsis.Biomedicines · 2026Article
- Risk Factors and Predictive Value of Sepsis in Patients with Liver Abscess.Infection and drug resistance · 2026Article
- The complex inflammatory indexes predict the prognostic risk for patients with acute coronary syndrome undergoing percutaneous coronary intervention.BMC immunology · 2025Article
- An individualized nomogram for predicting risk of sepsis in patients with pyogenic liver abscesses: a 10 years retrospective analysis.Frontiers in medicine · 2025Article
- Prognostic risk factors for pyogenic liver abscess caused by Klebsiella pneumoniae.BMC gastroenterology · 2024Article
- Assessment of leukocyte and systemic inflammation index ratios in dyslipidemia patients with dry eye disease: a retrospective case‒control study.Lipids in health and disease · 2024Article
- Correlation between novel inflammatory markers and carotid atherosclerosis: A retrospective case-control study.PloS one · 2024Article
- Predicting immunoglobulin resistance in Kawasaki disease: an assessment of neutrophil to lymphocyte platelet ratio.Italian journal of pediatrics · 2022Article
- The Prognostic Value of Hematologic Inflammatory Markers in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- The Immunothrombotic Phenotype: Early Inflammatory and Hematologic Markers that Identify Children at Increased Risk of Avascular Necrosis Following Septic Arthritis.JB & JS open accessArticle
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6 authors.
Funding
Abstract
objectiveThe purpose of the current study was to evaluate the association between C-reactive protein-to-platelet ratio (CPR), neutrophil-to-lymphocyte*platelet ratio (NLPR) and fibrinogen-to-platelet ratio (FPR) and the prognoses of pyogenic liver abscess (PLA) patients.
methodsA cohort of 372 patients with confirmed PLA were enrolled in this retrospective study between 2015 and 2021. Laboratory data were collected on admission within 24 h. The demographic characteristics and clinical features were recorded. Risk factors for outcomes of PLA patients were determined via multivariate logistic regression analyses, and optimal cut-off values were estimated by using the receiver operating characteristic (ROC) curve analysis.
resultsOut of 372 patients, 57.8% were men, 80 (21.5%) developed sepsis, and 33 (8.9%) developed septic shock. The levels of CPR, NLPR and FPR were significantly increased in the development of sepsis, and prolonged hospital stays in PLA patients. The multivariate logistic regression analysis indicated that the CPR (OR: 2.262, 95% CI: 1.586-3.226, p < 0.001), NLPR (OR: 1.118, 95% CI: 1.070-1.167, p < 0.001) and FPR (OR: 1.197, 95% CI: 1.079-1.329, p = 0.001) were independent risks of PLA patients with sepsis, and NLPR (OR: 1.019, 95% CI: 1.004-1.046, p = 0.019) was shown to be an independent predictor of prolonged hospital stays. The ROC curve results showed that the three biomarkers had different predictive values, and CPR proved to work best, with a ROC value of 0.851 (95% CI: 0.807-0.896, p < 0.001) for sepsis.
conclusionHigher levels of CPR, NLPR and FPR were associated with a higher risk of poor outcomes. Moreover, a high CPR level performed best when predicting the clinical outcome in PLA patients.
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