Evidence map›Paper›PMID 35864377›Full record

ArticleDermatology and therapy2022

Demographic and Clinical Factors Associated with Patient-Reported Remission in Psoriatic Arthritis.

George Gondo, Megan Mosca, Julie Hong, Emanual Maverakis, Joseph F Merola, April W Armstrong, Tina Bhutani, Stacie J Bell, Wilson Liao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dermatology and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

George GondoNational Psoriasis Foundation, Portland, OR, USA.ORCID http://orcid.org/0000-0002-6468-0397
Megan MoscaUniversity of California at San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-9030-1058
Julie HongUniversity of California at San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-6568-9345
Emanual MaverakisUniversity of California at Davis, Sacramento, CA, USA.ORCID http://orcid.org/0000-0002-6294-6294
Joseph F MerolaBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-6514-4353
April W ArmstrongUniversity of Southern California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-0064-8707
Tina BhutaniUniversity of California at San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-8187-1024
Stacie J BellOpsis Health/Global Nutrition Project, Golden, CO, USA.ORCID http://orcid.org/0000-0002-9987-567X
Wilson LiaoUniversity of California at San Francisco, San Francisco, CA, USA. Wilson.liao@ucsf.edu.ORCID http://orcid.org/0000-0001-7883-6439
Brigham and Women's Hospital · USNational Psoriasis Foundation · USUniversity of California, Davis · USUniversity of California, San Francisco · USUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAchievement of remission in psoriatic arthritis is a key goal for patients and clinicians, yet definitions of remission may vary. Previous efforts have utilized multidomain measures such as minimal disease activity that assess the status of joints, skin, and function to determine current level of psoriatic arthritis (PsA) disease activity. The goal of this study is to identify factors associated with patient-reported psoriatic arthritis remission.

methodsThe National Psoriasis Foundation conducted a cross-sectional study using an online survey of a random stratified sample of 1570 individuals with psoriatic disease in the USA. Participants were asked about a provider diagnosis of psoriasis and/or psoriatic arthritis, comorbid conditions, and psoriatic arthritis impact and disease activity, and demographic questions. All participants reporting a physician-given diagnosis of psoriatic arthritis were asked if they felt their psoriatic arthritis was in remission ("Do you feel your psoriatic arthritis is in remission?" Yes/No/Unsure) and, if so, length of remission. Individuals with psoriasis and psoriatic arthritis reporting a body surface area impacted by psoriasis 3% or less were asked if they felt their psoriasis was in remission. Psoriatic arthritis disease activity and impact was assessed using the nine-question Psoriatic Arthritis Impact of Disease (PsAID-9) instrument and a global PsA-related quality of life question. PsAID-9 scores ≤ 4 were used to indicate acceptable disease state. Multivariate logistic regression was used to identify factors associated with patient-perceived PsA remission.

resultsOf 834 participants with PsA, including 76 (4.8%) with PsA without skin involvement ever, 144 (17.3%) felt their psoriatic arthritis was in remission, with an average remission duration of 43 months. Of those in remission, 116 (78.4%) reported currently using a treatment for their PsA, with most (75.7%) reporting using a biologic therapy for their PsA in the past 12 months. Multivariate logistic regression revealed that patient-perceived psoriatic arthritis remission was independently associated with experiencing acceptable disease state (PsAID-9 ≤ 4), perception of psoriasis remission, lower impact of PsA on global quality of life, and non-white race. Age, sex, body mass index, or biologic use in the last 12 months were not associated with patient-reported PsA remission.

conclusionOverall, patient perception of PsA remission was most strongly associated with patient-reported psoriasis remission.

Indexed as

PsoriasisPsoriatic arthritisQuality of lifeRemissionTreat-to-target

Identifiers

PMID35864377
PMCPMC9357585
OpenAlexW4286494008

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.