Evidence map›Paper›PMID 35864290›Full record

SynthesisScientific reports2022

The impact of preoperative oral nutrition supplementation on outcomes in patients undergoing gastrointestinal surgery for cancer in low- and middle-income countries: a systematic review and meta-analysis.

Stephen R Knight, Ahmad U Qureshi, Thomas M Drake, Marie Carmela M Lapitan, Mayaba Maimbo, Edwin Yenli, Stephen Tabiri, Dhruva Ghosh, Pamela A Kingsley, Sudha Sundar and 12 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  16. Association ofIn vivo (Athens, Greece)
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 9 institutions in 7 countries.

Stephen R KnightCentre for Medical Informatics, Usher Institute, Nine Bioquarter, University of Edinburgh, Edinburgh, EH16 4UX, UK. stephenknight@doctors.org.uk.
Ahmad U QureshiDepartment of Surgery, Services Institute of Medical Sciences, Lahore, Pakistan.
Thomas M DrakeCentre for Medical Informatics, Usher Institute, Nine Bioquarter, University of Edinburgh, Edinburgh, EH16 4UX, UK.
Marie Carmela M LapitanDepartment of Surgery, National Institutes of Health, University of the Philippines, Manila, Philippines.
Mayaba MaimboDepartment of General Surgery, Kitwe Teaching Hospital, Kitwe, Zambia.
Edwin YenliDepartment of Surgery, School of Medicine, University for Development Studies, Tamale, Ghana.
Stephen TabiriDepartment of Surgery, School of Medicine, University for Development Studies, Tamale, Ghana.
Dhruva GhoshDepartment of Paediatric Surgery, Christian Medical College, Ludhiana, India.
Pamela A KingsleyDepartment of Radiation Oncology Department, Christian Medical College, Ludhiana, India.
Sudha SundarInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
Catherine ShawCentre for Medical Informatics, Usher Institute, Nine Bioquarter, University of Edinburgh, Edinburgh, EH16 4UX, UK.
Apple P ValparaisoDepartment of Surgery, National Institutes of Health, University of the Philippines, Manila, Philippines.
Aneel BhanguInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
Peter BrocklehurstClinical and Experimental Medicine, University of Birmingham, Birmingham, UK.
Laura MagillInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
Dion G MortonClinical and Experimental Medicine, University of Birmingham, Birmingham, UK.
John NorrieCentre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
Tracey E RobertsInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
Evropi TheodoratouCentre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.
Thomas G WeiserDepartment of Surgery, Stanford University, Stanford, USA.
Sorrel BurdenSchool of Health Sciences, University of Manchester, Manchester, UK.
Ewen M HarrisonCentre for Medical Informatics, Usher Institute, Nine Bioquarter, University of Edinburgh, Edinburgh, EH16 4UX, UK.
University of Birmingham · GBUniversity of Edinburgh · GBChristian Medical College · INUniversity for Development Studies · GHUniversity of the Philippines Manila · PHManchester Academic Health Science Centre · GBServices Institute of Medical Sciences · PKStanford University · USZambia Forestry College · ZM

Funding

Cancer Research UK 22804Cancer Research UK C31250/A22804Medical Research Council MR/S014527/1
6 · The paper itself

Abstract

Malnutrition is an independent predictor for postoperative complications in low- and middle-income countries (LMICs). We systematically reviewed evidence on the impact of preoperative oral nutrition supplementation (ONS) on patients undergoing gastrointestinal cancer surgery in LMICs. We searched EMBASE, Cochrane Library, Web of Science, Scopus, WHO Global Index Medicus, SciELO, Latin American and Caribbean Health Sciences Literature (LILACS) databases from inception to March 21, 2022 for randomised controlled trials evaluating preoperative ONS in gastrointestinal cancer within LMICs. We evaluated the impact of ONS on all postoperative outcomes using random-effects meta-analysis. Seven studies reported on 891 patients (446 ONS group, 445 control group) undergoing surgery for gastrointestinal cancer. Preoperative ONS reduced all cause postoperative surgical complications (risk ratio (RR) 0.53, 95% CI 0.46-0.60, P < 0.001, I

Indexed as

Digestive System Surgical ProceduresGastrointestinal NeoplasmsMalnutritionDeveloping CountriesDietary SupplementsHumansPostoperative Complications

Identifiers

PMID35864290
PMCPMC9304351
OpenAlexW4286491065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.