Evidence map›Paper›PMID 35864249›Full record

ReviewNature medicine2022

Syndemics and clinical science.

Emily Mendenhall, Brandon A Kohrt, Carmen H Logie, Alexander C Tsai

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Syndemic analysis of stroke in Indonesia.The Lancet regional health. Western Pacific · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Towards a 'people and nature' paradigm for biodiversity and infectious disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emily MendenhallEdmund A. Walsh School of Foreign Service, Georgetown University, Washington, DC, USA. em1061@georgetown.edu.ORCID http://orcid.org/0000-0002-5826-1321
Brandon A KohrtDepartment of Psychiatry, George Washington University, Washington, DC, USA.
Carmen H LogieFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-8035-433X
Alexander C TsaiCenter for Global Health and Mongan Institute, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0001-6397-7917

Funding

Soweto Syndemics: A Two-Phase Study of Surveillance and Co-Morbid ExperiencesR21TW010789 · FIC · GEORGETOWN UNIVERSITY · PI MENDENHALL, EMILY A · 2018 to 2020
$391k
FIC NIH HHS R21 TW010789
6 · The paper itself

Abstract

The theory of syndemics has received increasing attention in clinical medicine since the onset of the COVID-19 pandemic, due to the synergistic interactions of the disease with pre-existing political, structural, social and health conditions. In simple terms, syndemics are synergistically interacting epidemics that occur in a particular context with shared drivers. When policymakers ask why some communities have higher death rates from COVID-19 compared with other communities, those working from a syndemics framework argue that multiple factors synergistically work in tandem, and populations with the highest morbidity and mortality experience the greatest impact of these interactions. In this Perspective, we use specific case examples to illustrate these concepts. We discuss the emergence of syndemics, how epidemics interact, and what scientists, clinicians and policymakers can do with this information.

Indexed as

COVID-19SyndemicHumansPandemics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.