ReviewNature microbiology2022
Harnessing the microbiome to prevent global biodiversity loss.
Review in Nature microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
120 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Harnessing the Gut Microbiome in Cancer Immunotherapy: Mechanisms, Challenges, and Routes to Personalized Medicine-A Systematic Review.Technology in cancer research & treatmentPooled it
- Pharmacomicrobiomics-driven targeted drug delivery for precision microbiome modulation.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026Review
- Patterns of Functional Redundancy and Anaerobic Metabolic Potential Characterise the Skin Microbiome of a Critically Endangered Sawfish.Environmental microbiology · 2026Article
- Reply to 'Grounding microbial conservation in ecological principles'.Nature microbiology · 2026Article
- Contrasting Responses of Rhizosphere Bacterial and Fungal Communities ofMicroorganisms · 2026Article
- Soil microbial conservation cannot rely on above-ground biodiversity.Nature reviews. Microbiology · 2026Article
- Deficiency of Natural Plant-Derived Gut Metabolites Is a Potential Cause of Skeletal Deformities in Captive-Bred Green Peafowl (Animals : an open access journal from MDPI · 2026Article
- Coral-associated microbiome dynamics under thermal and pollution stress.Conservation biology : the journal of the Society for Conservation Biology · 2026Article
- Predicting the seed microbiome using phylogeny-driven machine learning.Environmental microbiome · 2026Article
- Towards Key Principles of Host-Associated Microbiome Assembly.Ecology letters · 2026Article
- Ecosystem technology (ecotech): Harnessing natural processes to address global challenges.Science advances · 2026Review
- Microbes first into the life rafts: preserving microbiomes to secure health in degrading ecosystems.Sustainable microbiology · 2026Article
- Plant-pollinator interactions and floral and nectar traits shape the diversity of the nectar mycobiome.Scientific reports · 2026Article
- Article
- Review
- Patterns of Orchid Diversity and Their Potential Habitat Under Climate Change in Chongqing, China.Biology · 2026Article
- Developing global goals for soil health research and action: report on the "Soil Stars Heligan Summit," The Lost Gardens of Heligan, UK, March 2026.Sustainable microbiology · 2026Article
- Engineering synthetic microbial communities for soil restoration: from rational design to multi-scale biogeochemical applications.Frontiers in microbiology · 2026Review
- Bacterial disease in seaweed aquaculture: pathogen diversity and future solutions.Journal of applied phycology · 2026Review
- Article
60 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Global biodiversity loss and mass extinction of species are two of the most critical environmental issues the world is currently facing, resulting in the disruption of various ecosystems central to environmental functions and human health. Microbiome-targeted interventions, such as probiotics and microbiome transplants, are emerging as potential options to reverse deterioration of biodiversity and increase the resilience of wildlife and ecosystems. However, the implementation of these interventions is urgently needed. We summarize the current concepts, bottlenecks and ethical aspects encompassing the careful and responsible management of ecosystem resources using the microbiome (termed microbiome stewardship) to rehabilitate organisms and ecosystem functions. We propose a real-world application framework to guide environmental and wildlife probiotic applications. This framework details steps that must be taken in the upscaling process while weighing risks against the high toll of inaction. In doing so, we draw parallels with other aspects of contemporary science moving swiftly in the face of urgent global challenges.
Indexed as
Identifiers
35864220What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.