Evidence map›Paper›PMID 35864165›Full record

ArticleNature structural & molecular biology2022

Coupling of distant ATPase domains in the circadian clock protein KaiC.

Jeffrey A Swan, Colby R Sandate, Archana G Chavan, Alfred M Freeberg, Diana Etwaru, Dustin C Ernst, Joseph G Palacios, Susan S Golden, Andy LiWang, Gabriel C Lander and 1 more

Open access · greenAbstract read
In one paragraph

Article in Nature structural & molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. An intron-based timer for circadian rhythms.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The cyanobacterial circadian clock.Npj biological timing and sleep · 2025
    Review
  10. Article
  11. The inner workings of an ancient biological clock.Trends in biochemical sciences · 2024
    Review
  12. Structure-function relationship of KaiC around dawn.Biophysics and physicobiology · 2024
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jeffrey A Swan *Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA, USA.
Colby R Sandate *Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-8758-5931
Archana G ChavanDepartment of Chemistry and Biochemistry, University of California, Merced, CA, USA.
Alfred M FreebergDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, CA, USA.
Diana EtwaruDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, CA, USA.
Dustin C ErnstCenter for Circadian Biology, University of California, San Diego, La Jolla, CA, USA.
Joseph G PalaciosDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, CA, USA.
Susan S GoldenCenter for Circadian Biology, University of California, San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-4264-7019
Andy LiWangDepartment of Chemistry and Biochemistry, University of California, Merced, CA, USA.ORCID http://orcid.org/0000-0003-4741-6946
Gabriel C LanderDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA. glander@scripps.edu.ORCID http://orcid.org/0000-0003-4921-1135
Carrie L PartchDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, CA, USA. cpartch@ucsc.edu.ORCID http://orcid.org/0000-0002-4677-2861
University of California, Santa Cruz · USScripps Research Institute · USUniversity of California, Merced · USUniversity of California San Diego · US

Funding

Undergraduate Summer Research Experience: Molecular and cellular mechanisms of circadian timekeeping in a prokaryote modelR35GM118290 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GOLDEN, SUSAN S · 2016 to 2025
$6.7M
IMPACTING MITOCHONDRIAL FUNCTION THROUGH ALTERED PROTEASE ACTIVITYR01NS095892 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI WISEMAN, ROCKLAND LUKE · 2016 to 2025
$5.3M
Structures and mechanisms of circadian rhythms from cyanobacteria to humansR35GM141849 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI PARTCH, CARRIE L · 2021 to 2025
$4.6M
The Linchpin that Joins the Circadian Oscillator to Clock OutputR01GM107521 · NIGMS · UNIVERSITY OF CALIFORNIA, MERCED · PI LIWANG, ANDY · 2014 to 2021
$2.8M
Atomic resolution analysis of timekeeping by a protein-based circadian clockR01GM121507 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI PARTCH, CARRIE L · 2017 to 2020
$1.8M
Development of a pipeline for parallel elucidation of protein structuresR21GM142196 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI LANDER, GABRIEL C · 2021 to 2022
$488k
Examining the impact arrhythmic gene expression has on fitness in cyanobacteria possessing a complete circadian clockF32GM130070 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ERNST, DUSTIN C · 2018 to 2020
$129k
NIGMS NIH HHS F32 GM130070NIGMS NIH HHS R01 GM107521NIGMS NIH HHS R01 GM121507NIGMS NIH HHS R21 GM142196NIGMS NIH HHS R35 GM118290NIGMS NIH HHS R35 GM141849NINDS NIH HHS R01 NS095892
6 · The paper itself

Abstract

The AAA

Indexed as

Circadian ClocksSynechococcusAdenosine TriphosphatasesBacterial ProteinsCircadian RhythmCircadian Rhythm Signaling Peptides and ProteinsCLOCK ProteinsPhosphorylationAdenosine TriphosphatasesBacterial ProteinsCircadian Rhythm Signaling Peptides and ProteinsCLOCK Proteins

Identifiers

PMID35864165
PMCPMC9495280
OpenAlexW4286493435

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.