ArticleNature communications2022
A nationwide questionnaire study of post-acute symptoms and health problems after SARS-CoV-2 infection in Denmark.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 4 of them syntheses that pooled it.
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Who cites it
53 citing papers in PubMed, 4 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Global prevalence of post-COVID-19 condition (Long COVID): a systematic review and meta-analysis of observational studies.Frontiers in public health · 2026Pooled it
- Pooled it
- Excess risks of long COVID symptoms compared with identical symptoms in the general population: A systematic review and meta-analysis of studies with control groups.Journal of global health · 2024Pooled it
- Risk of long COVID main symptoms after SARS-CoV-2 infection: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Healthcare seeking with colorectal cancer symptoms-results from two Danish population-based surveys in 2012 and 2022.Scandinavian journal of primary health care · 2026Article
- Health-related quality of life in IBD patients with long COVID under China's normalized COVID-19 management.BMC infectious diseases · 2026Article
- A systematic scoping review and conceptual analysis of new-onset fibromyalgia manifestations after non-hospitalized COVID-19: empirics, definitions, methodologies, pathophysiology, mapping of literature, and knowledge gaps.Journal of translational medicine · 2026Article
- Immune-metabolic trajectories delineate subgroups in paediatric long COVID.Nature communications · 2026Article
- Risk factors for severe post-COVID condition in children, adolescents, and young adults.European journal of pediatrics · 2026Observational
- Risk of Sequelae Following COVID-19 Infection: A Nationwide Study Focusing on Risk Factors and Long-Term Impacts.Journal of clinical medicine · 2025Article
- Impact of long COVID phenotypes on quality of life following symptomatic omicron infection in Brazil: a machine learning analysis.BMC infectious diseases · 2025Observational
- Pathways in the brain, heart and lung influenced by SARS-CoV-2 NSP6 and SARS-CoV-2 regulated miRNAs: an in silico study hinting cancer incidence.Cardio-oncology (London, England) · 2025Article
- NETosis: A key player in autoimmunity, COVID-19, and long COVID.Journal of translational autoimmunity · 2025Review
- Considerations and experiences with healthcare-seeking during the first COVID-19 lockdown in Denmark.Scandinavian journal of primary health care · 2025Article
- Predictive Ability of Previous Pain and Disease Conditions on the Presentation of Post-COVID Pain in a Danish Cohort of Adult COVID-19 Survivors.European journal of pain (London, England) · 2025Article
- Data for action - description of the automated COVID-19 surveillance system in Denmark and lessons learnt, January 2020 to June 2024.Epidemiology and infection · 2025Article
- Prevalence of erectile dysfunction as long-COVID symptom in hospitalized Japanese patients.Scientific reports · 2025Article
- Unveiling the Oral Lesions, Dysgeusia and Osteonecrosis Related to COVID-19: A Comprehensive Systematic Review.Journal of clinical medicine · 2025Review
- Smoking status, symptom significance and healthcare seeking with lung cancer symptoms in the Danish general population.NPJ primary care respiratory medicine · 2025Article
- Observational
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A considerable number of individuals infected with SARS-CoV-2 continue to experience symptoms after the acute phase. Here, we report findings from a nationwide questionnaire study in Denmark including 61,002 RT-PCR confirmed SARS-CoV-2 cases and 91,878 test-negative controls aged 15-years or older. Six to twelve months after the test, the risks of 18 out of 21 symptoms were elevated among test-positives. The largest adjusted risk differences (RD) were observed for dysosmia (RD = 10.92%, 95% CI 10.68-11.21%), dysgeusia (RD = 8.68%, 95% CI 8.43-8.93%), fatigue/exhaustion (RD = 8.43%, 95%CI 8.14-8.74%), dyspnea (RD = 4.87%, 95% CI 4.65-5.09%) and reduced strength in arms/legs (RD = 4.68%, 95% CI 4.45-4.89%). During the period from the test and until completion of the questionnaire, new diagnoses of anxiety (RD = 1.15%, 95% CI 0.95-1.34%) or depression (RD = 1.00%, 95% CI 0.81-1.19%) were also more common among test-positives. Even in a population where the majority of test-positives were not hospitalized, a considerable proportion experiences symptoms up to 12 months after infection. Being female or middle-aged increases risks.
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