Evidence map›Paper›PMID 35863856›Full record

ArticleBMJ case reports2022

Whipple's disease unmasked by TNF inhibitor therapy for treatment of seronegative rheumatoid arthritis.

Fahad Mohammed, Muhannad Kurtom, Andrew Brant, Rahul Sampath

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Human genetics of Whipple's disease.Current opinion in rheumatology · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Fahad MohammedNeuroscience, Duke University Trinity College of Arts and Sciences, Durham, North Carolina, USA fsm10@duke.edu.ORCID http://orcid.org/0000-0002-4439-0405
Muhannad KurtomMedicine, UNC Health Blue Ridge, Morganton, North Carolina, USA.
Andrew BrantPathology, UNC Health Blue Ridge, Morganton, North Carolina, USA.
Rahul SampathInfectious Disease, UNC Health Blue Ridge, Morganton, North Carolina, USA.
University of North Carolina Health Care · USDuke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a patient with seronegative rheumatoid arthritis diagnosed with Whipple's disease following treatment of tumour necrosis factor inhibitor (TNFI) therapy. Whipple's disease should be considered in patients with seronegative rheumatoid arthritis and other unexplained multisystem illness. The TNFI therapy and immunosuppressive therapies can unmask latent Whipple's disease.

Indexed as

Arthritis, RheumatoidWhipple DiseaseHumansTumor Necrosis Factor InhibitorsTumor Necrosis Factor InhibitorsHepatitis and other GI infectionsInfection (gastroenterology)

Identifiers

PMID35863856
PMCPMC9310182
OpenAlexW4286512902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.