Evidence map›Paper›PMID 35863765›Full record

ArticleThorax2022

Assessment of formal tobacco treatment and smoking cessation in dual users of cigarettes and e-cigarettes.

Brendan T Heiden, Timothy B Baker, Nina Smock, Giang Pham, Jingling Chen, Laura J Bierut, Li-Shiun Chen

Open access · greenAbstract read
In one paragraph

Article in Thorax, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Brendan T HeidenDivision of Cardiothoracic Surgery, Department of Surgery, Washington University in St Louis School of Medicine, St Louis, Missouri, USA bheiden@wustl.edu.ORCID http://orcid.org/0000-0002-0116-7377
Timothy B BakerCenter for Tobacco Research and Intervention, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Nina SmockDepartment of Psychiatry, Washington University in St Louis School of Medicine, St Louis, Missouri, USA.
Giang PhamDepartment of Psychiatry, Washington University in St Louis School of Medicine, St Louis, Missouri, USA.
Jingling ChenDepartment of Psychiatry, Washington University in St Louis School of Medicine, St Louis, Missouri, USA.
Laura J BierutDepartment of Psychiatry, Washington University in St Louis School of Medicine, St Louis, Missouri, USA.
Li-Shiun ChenDivision of Public Health Sciences, Department of Surgery, Washington University in St Louis School of Medicine, St Louis, Missouri, USA.
Washington University in St. Louis · USUniversity of Wisconsin–Madison · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Translating Molecular and Clinical Data to Population Lung Cancer Risk AssessmentU19CA203654 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Rayjean J. Hung · 2017 to 2026
$23.7M
Washington University Implementation Science Center for Cancer Control (WU-ISCCC)P50CA244431 · NCI · WASHINGTON UNIVERSITY · PI BROWNSON, ROSS C, COLDITZ, GRAHAM A. · 2019 to 2023
$8.0M
BASIC SCIENCE RESEARCH TRAINING: CARDIOPULMONARY SURGERYT32HL007776 · NHLBI · WASHINGTON UNIVERSITY · PI DAMIANO, RALPH J · 1994 to 2020
$4.6M
Genetically Informed Smoking Cessation TrialR01DA038076 · NIDA · WASHINGTON UNIVERSITY · PI CHEN, LI-SHIUN · 2014 to 2018
$3.3M
NCI NIH HHS P30 CA091842NCI NIH HHS P50 CA244431NCI NIH HHS U19 CA203654NHLBI NIH HHS T32 HL007776NIDA NIH HHS R01 DA038076
6 · The paper itself

Abstract

backgroundThe utility of electronic cigarettes ('e-cigarettes') as a smoking cessation adjunct remains unclear. Similarly, it is unclear if formal tobacco treatment (pharmacotherapy and/or behavioural support) augments smoking cessation in individuals who use both cigarettes and e-cigarettes.

methodsWe performed a longitudinal cohort study of adult outpatients evaluated in our tertiary care medical centre (6/2018-6/2020). E-cigarette use, smoking status and formal tobacco treatment (deterrent pharmacotherapy and/or behavioural support) were assessed in 6-month blocks (eg, cohort 1 (C1)=6/2018-12/2018, C2=1/2019-6/2019 and so on) using our electronic health record. We assessed the relationship between e-cigarette use (either with or without formal tobacco treatment) and point prevalence of smoking cessation at 6 and 12 months.

results111 823 unique patients were included in the study. The prevalence of dual use of cigarettes and e-cigarettes increased significantly over the study period (C1=0.8%; C2=1.1%; C3=1.8%; C4=2.3%; p<0.001). The prevalence of smoking cessation at 12 months was higher among e-cigarette users (20.8%) compared with non-users (16.8%) (risk difference, 4.0% (95% CI 2.5% to 5.5%); adjusted relative risk (aRR) 1.354, 95% CI 1.252 to 1.464, p<0.0001). Further, among dual users of cigarettes and e-cigarettes, the prevalence of smoking cessation at 12 months was higher among individuals who received tobacco treatment (29.1%) compared with individuals who did not receive tobacco treatment (19.6%) (risk difference, 9.5% (95% CI, 4.6% to 14.4%); aRR 1.238, 95% CI 1.071 to 1.432, p=0.004).

interpretationThese results suggest that dual users of cigarettes and e-cigarettes benefit from formal tobacco treatment. Clinicians should consider offering formal tobacco treatment to such patients, though future trials are needed.

Indexed as

smoking cessationtobacco and the lungtobacco control

Identifiers

PMID35863765
PMCPMC9852353
OpenAlexW4286503980

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.