SynthesisSexual health2022
Effectiveness and acceptability of conversational agents for sexual health promotion: a systematic review and meta-analysis.
Synthesis in Sexual health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Dating Applications as HIV Prevention Ecosystems in the Era of Digital Sexual Networks.Infectious disease reports · 2026Article
- Japanese Health Information Technology Usability Evaluation Scale for Sexually Transmitted Infection-Related Chatbots: Development and Psychometric Validation Study.JMIR human factors · 2026Article
- Article
- Physicians' expectations of the use of conversational agents in healthcare: a qualitative study.BMC health services research · 2026Article
- Chatbots as frontline educators in sexual reproductive health rights: evidence, limitations, and ethical considerations.Frontiers in digital health · 2026Article
- Toward safer digital sexual health communication: evaluating the public health reliability of large language model responses on sexually transmitted infections.Frontiers in public health · 2026Article
- Use of Artificial Intelligence-Assisted Conversational Agents to Improve Patient Experience Related to Physicians: Cross-Sectional Study in China.Journal of medical Internet research · 2025Article
- User Input in the Development of Digital Sexual Health Tools: A Scoping Review and Guidance for Tool Developers.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Current Landscape and Future Directions for Mental Health Conversational Agents for Youth: Scoping Review.JMIR medical informatics · 2025Article
- Change in sexual and reproductive health knowledge among young women using the conversational agent "Nthabi" in Lesotho: a clinical trial.BMC global and public health · 2024Article
- Effectiveness and User Experience of a Smoking Cessation Chatbot: Mixed Methods Study Comparing Motivational Interviewing and Confrontational Counseling.Journal of medical Internet research · 2024Article
- Roles, Users, Benefits, and Limitations of Chatbots in Health Care: Rapid Review.Journal of medical Internet research · 2024Review
- Usability and Acceptability of a Conversational Agent Health Education App (Nthabi) for Young Women in Lesotho: Quantitative Study.JMIR human factors · 2024Article
- Change in Sexual and Reproductive Health Knowledge among Young Women Using the Conversational Agent "Nthabi" in Lesotho: A Clinical Trial.Research square · 2023Article
- The Impact of Generative Conversational Artificial Intelligence on the Lesbian, Gay, Bisexual, Transgender, and Queer Community: Scoping Review.Journal of medical Internet research · 2023Article
- "But can chatbots understand sex?" Attitudes towards artificial intelligence chatbots amongst sexual and reproductive health professionals: An exploratory mixed-methods study.International journal of STD & AIDS · 2023Article
- Chatbots to Improve Sexual and Reproductive Health: Realist Synthesis.Journal of medical Internet research · 2023Review
- SNapp, a Tailored Smartphone App Intervention to Promote Walking in Adults of Low Socioeconomic Position: Development and Qualitative Pilot Study.JMIR formative research · 2023Article
- Investigating Patients' Continuance Intention Toward Conversational Agents in Outpatient Departments: Cross-sectional Field Survey.Journal of medical Internet research · 2022Article
- Safety-focused development and evaluation of an LLM sexual well-being chatbot for women: A methods-focused feasibility study.Digital healthArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Digital health interventions for sexual health promotion have evolved considerably alongside innovations in technology. Despite these efforts, studies have shown that they do not consistently result in the desired sexual health outcomes. This could be attributed to low levels of user engagement, which can hinder digital health intervention effectiveness, as users do not engage with the system enough to be exposed to the intervention components. It has been suggested that conversational agents (automated two-way communication systems e.g. Alexa) have the potential to overcome the limitations of prior systems and promote user engagement through the increased interactivity offered by bidirectional, natural language-based interactions. The present review, therefore, provides an overview of the effectiveness and user acceptability of conversational agents for sexual health promotion. A systematic search of seven databases provided 4534 records, and after screening, 31 articles were included in this review. A narrative synthesis of results was conducted for effectiveness and acceptability outcomes, with the former supplemented by a meta-analysis conducted on a subset of studies. Findings provide preliminary support for the effectiveness of conversational agents for promoting sexual health, particularly treatment adherence. These conversational agents were found to be easy to use and useful, and importantly, resulted in high levels of satisfaction, use and intentions to reuse, whereas user evaluations regarding the quality of information left room for improvement. The results can inform subsequent efforts to design and evaluate these interventions, and offer insight into additional user experience constructs identified outside of current technology acceptance models, which can be incorporated into future theoretical developments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.