Evidence map›Paper›PMID 35863755›Full record

ArticleOrganic letters2022

Green-Emitting 4,5-Diaminonaphthalimides in Activity-Based Probes for the Detection of Thrombin.

Maciej Krzeszewski, Sylwia Modrzycka, Manon H E Bousquet, Denis Jacquemin, Marcin Drąg, Daniel T Gryko

Abstract read
In one paragraph

Article in Organic letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maciej KrzeszewskiInstitute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, Warsaw 01-224, Poland.
Sylwia ModrzyckaDepartment of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology, Wybrezeże Wyspiańskiego 27, Wrocław 50-370, Poland.
Manon H E BousquetCEISAM UMR CNRS 6230, Nantes University, Nantes 44000, France.ORCID 0000-0002-4661-410X
Denis JacqueminCEISAM UMR CNRS 6230, Nantes University, Nantes 44000, France.ORCID 0000-0002-4217-0708
Marcin DrągDepartment of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology, Wybrezeże Wyspiańskiego 27, Wrocław 50-370, Poland.
Daniel T GrykoInstitute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, Warsaw 01-224, Poland.ORCID 0000-0002-2146-1282

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natures of electron-donating groups as well as the bridge between them determine the fate of substituted 1,8-naphthalimide molecules in the excited state. An activity-based probe constructed from a selective peptide sequence, a reactive warhead, and the brightest green-emitting fluorophore displays impressive performance for thrombin protease detection in a newly constructed series of 1,8-naphthalimides.

Indexed as

NaphthalimidesThrombinElectronsFluorescent DyesFluorescent DyesNaphthalimidesThrombin

Identifiers

PMID35863755
PMCPMC9361357

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.