Evidence map›Paper›PMID 35863699›Full record

ArticleThe Journal of molecular diagnostics : JMD2022

Clinical Performance Characteristics of the Swift Normalase Amplicon Panel for Sensitive Recovery of Severe Acute Respiratory Syndrome Coronavirus 2 Genomes.

Lasata Shrestha, Michelle J Lin, Hong Xie, Margaret G Mills, Shah A Mohamed Bakhash, Vinod P Gaur, Robert J Livingston, Jared Castor, Emily A Bruce, Jason W Botten and 4 more

Abstract read
In one paragraph

Article in The Journal of molecular diagnostics : JMD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
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  7. Outcomes in Hematopoietic Cell Transplant and Chimeric Antigen Receptor T-Cell Therapy Recipients With Pre-Cellular Therapy SARS-CoV-2 Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lasata ShresthaDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Michelle J LinDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Hong XieDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Margaret G MillsDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Shah A Mohamed BakhashDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Vinod P GaurDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Robert J LivingstonDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Jared CastorDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Emily A BruceDepartment of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont.
Jason W BottenDepartment of Medicine, University of Vermont, Burlington, Vermont.
Meei-Li HuangDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington.
Keith R JeromeDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Alexander L GreningerDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. Electronic address: agrening@uw.edu.
Pavitra RoychoudhuryDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. Electronic address: proychou@uw.edu.

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI CONNIE L CELUM · 1988 to 2026
$104.9M
Vermont Immunology/Infectious Diseases CenterP30GM118228 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BUDD, RALPH C · 2016 to 2021
$6.8M
High-Performance Compute Cluster for Comprehensive Cancer and Infectious Diseases ResearchS10OD028685 · OD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BRADLEY, PHILIP · 2020 to 2020
$2.0M
NIAID NIH HHS P30 AI027757NIGMS NIH HHS P30 GM118228NIH HHS S10 OD028685
6 · The paper itself

Abstract

Amplicon-based sequencing methods are central in characterizing the diversity, transmission, and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but need to be rigorously assessed for clinical utility. Herein, we validated the Swift Biosciences' SARS-CoV-2 Swift Normalase Amplicon Panels using remnant clinical specimens. High-quality genomes meeting our established library and sequence quality criteria were recovered from positive specimens, with 95% limit of detection of 40.08 SARS-CoV-2 copies/PCR. Breadth of genome recovery was evaluated across a range of C

Indexed as

COVID-19SARS-CoV-2Genome, ViralHumansRNA, ViralWhole Genome SequencingRNA, Viral

Identifiers

PMID35863699
PMCPMC9290336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.