ArticleClinical and experimental emergency medicine2022
Fatal arrhythmia following ingestion of hawthorn root (Crataegus pubescens) extract: a case report.
Article in Clinical and experimental emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- When herbal supplements cause heart problems: Clinical case report and forensic toxicological analysis.Toxicology reports · 2026Article
- Analysis of Adverse Reactions Associated with the Use ofPharmaceuticals (Basel, Switzerland) · 2024Article
- Interactions Between Depression, Alcohol Intake, and Smoking on the Risk of Acute Coronary Syndrome.Psychiatry investigation · 2024Article
- Tejocote Root's Role in Symptomatic Mobitz Type 1 Heart Block: A Compelling Case Report.Cureus · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of extracts from the hawthorn plant as cardiovascular agents dates back to the 1st century; recently, they have also been made available online as weight loss aids. Herein, we present a case of intentional intoxication with hawthorn root extract (HRE) in an adult patient that resulted in death. A 20-year-old female patient, who was clinically diagnosed with depression, developed hypotension, bradycardia, and depressed consciousness after ingestion of this extract. An electrocardiogram recorded a sinus arrest with a slow nodal rhythm, which rapidly deteriorated, leading to cardiac arrest. This case report illustrates the potentially fatal consequences of HRE for which the constituents have not yet been characterized. All physicians, especially those in the emergency department, should be aware of the dangerous, even potentially fatal interactions of HRE with prescription medications.
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