Evidence map›Paper›PMID 35863111›Full record

ArticleAnalytical chemistry2022

Single-Cell Mass Spectrometry Enables Insight into Heterogeneity in Infectious Disease.

Tra D Nguyen, Yunpeng Lan, Shelley S Kane, Jacob J Haffner, Renmeng Liu, Laura-Isobel McCall, Zhibo Yang

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

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  15. The intersection of hostMicrobiology and molecular biology reviews : MMBR · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tra D NguyenDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.
Yunpeng LanDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.
Shelley S KaneDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.
Jacob J HaffnerLaboratories of Molecular Anthropology and Microbiome Research, University of Oklahoma, Norman, Oklahoma 73019, United States.
Renmeng LiuDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.
Laura-Isobel McCallDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.
Zhibo YangDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, United States.ORCID 0000-0003-0370-7450
University of Oklahoma · US

Funding

UC San Diego RAPID Faculty Development Program in Infectious DiseasesR25AI147376 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ADRIANA H TREMOULET, Joann Trejo · 2020 to 2026
$2.5M
From Single Cells to Tissues: a Novel Mass Spectrometry Approach for BioanalysisR01GM116116 · NIGMS · UNIVERSITY OF OKLAHOMA · PI YANG, ZHIBO · 2015 to 2019
$1.5M
NIAID NIH HHS R25 AI147376NIGMS NIH HHS R01 GM116116
6 · The paper itself

Abstract

Cellular heterogeneity is generally overlooked in infectious diseases. In this study, we investigated host cell heterogeneity during infection with

Indexed as

Chagas DiseaseCommunicable DiseasesTrypanosoma cruziAnimalsMammalsMass SpectrometryMetabolomics

Identifiers

PMID35863111
PMCPMC10064790
OpenAlexW4286382916

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.