Evidence map›Paper›PMID 35863024›Full record

ArticleMicrobiology spectrum2022

Nitrite Promotes ROS Production to Potentiate Cefoperazone-Sulbactam-Mediated Elimination to Lab-Evolved and Clinical-Evolved Pseudomonas aeruginosa.

Su-Fang Kuang, Xia Li, Ding-Yun Feng, Wen-Bin Wu, Hui Li, Bo Peng, Xuan-Xian Peng, Zhuang-Gui Chen, Tian-Tuo Zhang

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  6. Structural characteristics, functions, and counteracting strategies of biofilms inComputational and structural biotechnology journal · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Su-Fang KuangThe Third Affiliated Hospital and State Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen Universitygrid.12981.33, University City, Guangzhou, People's Republic of China.
Xia LiThe Third Affiliated Hospital and State Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen Universitygrid.12981.33, University City, Guangzhou, People's Republic of China.
Ding-Yun FengThe Third Affiliated Hospital and State Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen Universitygrid.12981.33, University City, Guangzhou, People's Republic of China.
Wen-Bin WuThe Third Affiliated Hospital and State Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen Universitygrid.12981.33, University City, Guangzhou, People's Republic of China.
Hui LiThe Third Affiliated Hospital and State Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen Universitygrid.12981.33, University City, Guangzhou, People's Republic of China.ORCID 0000-0003-2600-4838
Bo PengThe Third Affiliated Hospital and State Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen Universitygrid.12981.33, University City, Guangzhou, People's Republic of China.
Xuan-Xian PengThe Third Affiliated Hospital and State Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen Universitygrid.12981.33, University City, Guangzhou, People's Republic of China.
Zhuang-Gui ChenThe Third Affiliated Hospital and State Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen Universitygrid.12981.33, University City, Guangzhou, People's Republic of China.
Tian-Tuo ZhangThe Third Affiliated Hospital and State Key Laboratory of Bio-Control, School of Life Sciences, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Sun Yat-sen Universitygrid.12981.33, University City, Guangzhou, People's Republic of China.ORCID 0000-0002-9239-0434
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cefoperazone-sulbactam (SCF)-resistant Pseudomonas aeruginosa poses a big challenge in the use of SCF to treat infection caused by the pathogen. We have recently shown exogenous nitrite-enabled killing of naturally and artificially evolved Pseudomonas aeruginosa strains (AP-R

Indexed as

CefoperazoneSulbactamAcetylcysteineAnti-Bacterial AgentsFuraldehydeHumansHydrogen PeroxideNADNitritesOxidoreductasesPseudomonas aeruginosaPyruvatesReactive Oxygen SpeciesAcetylcysteineAnti-Bacterial AgentsCefoperazoneFuraldehydeHydrogen PeroxideNADNitritesOxidoreductasesPyruvatesReactive Oxygen SpeciesSulbactamantibiotic resistancecefoperazone-sulbactamelectron transport chainnitritePseudomonas aeruginosareprogramming metabolomicsthe pyruvate cycle

Identifiers

PMID35863024
PMCPMC9430864
OpenAlexW4284697247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.