Evidence map›Paper›PMID 35862816›Full record

ArticlemSphere2022

Tight Complex Formation of the Fumarate Sensing DcuS-DcuR Two-Component System at the Membrane and Target Promoter Search by Free DcuR Diffusion.

Stefaniya Gencheva, Simon Dersch, Kristin Surmann, Mathias Wernet, Luis Antelo, Elke Hammer, Peter L Graumann, Nadja Hellmann, Gottfried Unden

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Stefaniya GenchevaInstitute for Molecular Physiology; Microbiology and Biotechnology, Johannes Gutenberg-University, Mainz, Germany.
Simon DerschDepartment of Chemistry, and Centre for Synthetic Microbiology, SYNMIKRO, Philipps-University Marburg, Marburg.
Kristin SurmannDepartment of Functional Genomics, Center for Functional Genomics of Microbes, University Medicine Greifswald, Greifswald, Germany.
Mathias WernetInstitute for Molecular Physiology; Microbiology and Biotechnology, Johannes Gutenberg-University, Mainz, Germany.
Luis AnteloInstitute for Molecular Physiology; Microbiology and Biotechnology, Johannes Gutenberg-University, Mainz, Germany.
Elke HammerDepartment of Functional Genomics, Center for Functional Genomics of Microbes, University Medicine Greifswald, Greifswald, Germany.
Peter L GraumannDepartment of Chemistry, and Centre for Synthetic Microbiology, SYNMIKRO, Philipps-University Marburg, Marburg.ORCID 0000-0002-8033-5171
Nadja HellmannDepartment of Chemistry, Biochemistry, Johannes Gutenberg-University, Mainz, Germany.
Gottfried UndenInstitute for Molecular Physiology; Microbiology and Biotechnology, Johannes Gutenberg-University, Mainz, Germany.ORCID 0000-0003-4906-1835
Johannes Gutenberg University Mainz · DELoewe Center for Synthetic Microbiology · DEUniversitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Signaling of two-component systems by phosphoryl transfer requires interaction of the sensor kinase with the response regulator. Interaction of the C4-dicarboxylate-responsive and membrane-integral sensor kinase DcuS with the response regulator DcuR was studied.

Indexed as

DNA-Binding ProteinsEscherichia coli ProteinsProtein KinasesTranscription FactorsDicarboxylic Acid TransportersDNA, BacterialEscherichia coliFumaratesGene Expression Regulation, BacterialPromoter Regions, GeneticDcuR protein, E coliDcuS protein, E coliDicarboxylic Acid TransportersDNA, BacterialDNA-Binding ProteinsEscherichia coli ProteinsFumaratesProtein KinasesTranscription Factorsbacteriacomplex formationDcuS-DcuRsensor complexsensor kinasetwo-component system

Identifiers

PMID35862816
PMCPMC9429925
OpenAlexW4284899173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.