Evidence map›Paper›PMID 35862800›Full record

ArticlemSphere2022

Use of the Iron-Responsive

Yinhe Mao, Norma V Solis, Anupam Sharma, Max V Cravener, Scott G Filler, Aaron P Mitchell

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Two Ume6 target gene classes in the biofilm regulatory network ofbioRxiv : the preprint server for biology · 2026
    Article
  2. Impact ofmSphere · 2026
    Article
  3. Article
  4. Hgt17-Adr1 Relationship inJournal of fungi (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yinhe MaoDepartment of Microbiology, University of Georgiagrid.213876.9, Athens, Georgia, USA.
Norma V SolisLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
Anupam SharmaDepartment of Microbiology, University of Georgiagrid.213876.9, Athens, Georgia, USA.
Max V CravenerDepartment of Microbiology, University of Georgiagrid.213876.9, Athens, Georgia, USA.
Scott G FillerLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, USA.
Aaron P MitchellDepartment of Microbiology, University of Georgiagrid.213876.9, Athens, Georgia, USA.ORCID 0000-0002-0868-4000
University of Georgia · USUCLA Medical Center · US

Funding

C. albicans invasion and proliferation during oral infectionR01DE026600 · NIDCR · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G, MITCHELL, AARON P · 2017 to 2021
$3.0M
Endothelial invasion by yeast-phase CandidaR01AI124566 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G, MITCHELL, AARON P · 2016 to 2020
$2.7M
Functional Analysis of Natural Variation in the Pathogen Candida albicansR01AI146103 · NIAID · UNIVERSITY OF GEORGIA · PI MITCHELL, AARON P · 2019 to 2023
$2.6M
NIAID NIH HHS R01 AI124566NIAID NIH HHS R01 AI146103NIDCR NIH HHS R01 DE026600
6 · The paper itself

Abstract

Engineered conditional gene expression is used in appraisal of gene function and pathway relationships. For pathogens like the fungus Candida albicans, conditional expression systems are most useful if they are active in the infection environment and if they can be utilized in multiple clinical isolates. Here, we describe such a system. It employs the

Indexed as

Candida albicansHyphaeAnimalsFungal ProteinsGene Expression Regulation, FungalIronMiceFungal ProteinsIronCandida albicansgene expressiongeneticshyphal development

Identifiers

PMID35862800
PMCPMC9429880
OpenAlexW4285727069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.