Evidence map›Paper›PMID 35862787›Full record

ArticlemBio2022

Genomic Diversity across Candida auris Clinical Isolates Shapes Rapid Development of Antifungal Resistance

Laura S Burrack, Robert T Todd, Natthapon Soisangwan, Nathan P Wiederhold, Anna Selmecki

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Detection of "hidden" mitotic crossovers by long-read DNA sequencing.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  5. Molecular Epidemiology ofOpen forum infectious diseases · 2026
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  6. Micafungin exposure drives multidrug resistance inbioRxiv : the preprint server for biology · 2026
    Article
  7. Recent Outbreaks, Resistance Trends, and Control Measures inJournal of fungi (Basel, Switzerland) · 2026
    Review
  8. Article
  9. Defining thebioRxiv : the preprint server for biology · 2026
    Article
  10. Article
  11. Deciphering the multidrug resistance paradigm inAntimicrobial agents and chemotherapy · 2026
    Review
  12. Review
  13. Review
  14. bioRxiv : the preprint server for biology · 2026
    Article
  15. Resistance gene mutations and phylogenetic relationships inFrontiers in cellular and infection microbiology · 2026
    Article
  16. Review
  17. Article
  18. Article
  19. Pathogens (Basel, Switzerland) · 2025
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Laura S BurrackGustavus Adolphus College, Department of Biology, Saint Peter, Minnesota, USA.ORCID 0000-0002-0821-0980
Robert T ToddUniversity of Minnesotagrid.17635.36, Department of Microbiology and Immunology, Minneapolis, Minnesota, USA.
Natthapon SoisangwanUniversity of Minnesotagrid.17635.36, Department of Microbiology and Immunology, Minneapolis, Minnesota, USA.
Nathan P WiederholdUniversity of Texas Health Science Center at San Antonio, Department of Pathology and Laboratory Medicine, Fungus Testing Laboratory, San Antonio, Texas, USA.ORCID 0000-0002-2225-5122
Anna SelmeckiUniversity of Minnesotagrid.17635.36, Department of Microbiology and Immunology, Minneapolis, Minnesota, USA.ORCID 0000-0003-3298-2400
University of Minnesota · USThe University of Texas Health Science Center at San Antonio · US

Funding

Aneuploidy and Acquired Antifungal Drug Resistance in Candida speciesR01AI143689 · NIAID · UNIVERSITY OF MINNESOTA · PI Anna M. Selmecki · 2020 to 2026
$3.2M
NIAID NIH HHS R01 AI143689
6 · The paper itself

Abstract

Antifungal drug resistance and tolerance pose a serious threat to global public health. In the human fungal pathogen, Candida auris, resistance to triazole, polyene, and echinocandin antifungals is rising, resulting in multidrug resistant isolates. Here, we use genome analysis and

Indexed as

Antifungal AgentsFluconazoleCandidaCandida aurisDrug Resistance, FungalGenomicsHumansMicrobial Sensitivity TestsAntifungal AgentsFluconazoleaneuploidyantifungal resistanceCandida aurisechinocandinfluconazolemultidrug resistance

Identifiers

PMID35862787
PMCPMC9426540
OpenAlexW4283817659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.