Evidence map›Paper›PMID 35862758›Full record

ArticlemBio2022

Ddp1 Cooperates with Ppx1 to Counter a Stress Response Initiated by Nonvacuolar Polyphosphate.

Liam McCarthy, Iryna Abramchuk, Gamal Wafy, Alix Denoncourt, Mathieu Lavallée-Adam, Michael Downey

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Liam McCarthyDepartment of Cellular and Molecular Medicine, University of Ottawagrid.28046.38, Ottawa, Ontario, Canada.
Iryna AbramchukOttawa Institute of Systems Biology, University of Ottawagrid.28046.38, Ottawa, Ontario, Canada.
Gamal WafyDepartment of Cellular and Molecular Medicine, University of Ottawagrid.28046.38, Ottawa, Ontario, Canada.
Alix DenoncourtDepartment of Cellular and Molecular Medicine, University of Ottawagrid.28046.38, Ottawa, Ontario, Canada.
Mathieu Lavallée-AdamOttawa Institute of Systems Biology, University of Ottawagrid.28046.38, Ottawa, Ontario, Canada.
Michael DowneyDepartment of Cellular and Molecular Medicine, University of Ottawagrid.28046.38, Ottawa, Ontario, Canada.ORCID 0000-0002-5234-6666
University of Ottawa · CA

Funding

CIHR PJT-148722CIHR PJT-174987
6 · The paper itself

Abstract

In diverse cells from bacterial to mammalian species, inorganic phosphate is stored in long chains called polyphosphate (polyP). These nearly universal polymers, ranging from three to thousands of phosphate moieties in length, are associated with molecular functions, including energy homeostasis, protein folding, and cell signaling. In many cell types, polyphosphate is concentrated in subcellular compartments or organelles. In the budding yeast Saccharomyces cerevisiae, polyP synthesis by the membrane-bound

Indexed as

Biological PhenomenaSaccharomyces cerevisiae ProteinsAnimalsDNA-Binding ProteinsHumansMammalsPolyphosphatesSaccharomyces cerevisiaeTranscription FactorsDNA-Binding ProteinsMSN2 protein, S cerevisiaeMSN4 protein, S cerevisiaePolyphosphatesSaccharomyces cerevisiae ProteinsTranscription FactorsHog1Msn2PKApolyPpolyphosphatePPKPpx1proteomicsstressstress responsevacuoleVtc4Yak1yeast

Identifiers

PMID35862758
PMCPMC9426566
OpenAlexW4284900278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.