Evidence map›Paper›PMID 35862750›Full record

ArticleAntimicrobial agents and chemotherapy2022

Genetic Diversity of Plasmodium falciparum and Distribution of Antimalarial Drug Resistance Mutations in Symptomatic and Asymptomatic Infections.

Elangwe M Sarah-Matio, Emilie Guillochon, Sandrine E Nsango, Luc Abate, Christelle M Ngou, Gaelle A Bouopda, Lionel B Feufack-Donfack, Albert N Bayibéki, Majoline Tchioffo Tsapi, Arthur Talman and 6 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Reversal of Chloroquine Resistance inInternational journal of molecular sciences · 2026
    Article
  5. Molecular Characterization ofTropical medicine and infectious disease · 2025
    Article
  6. Article
  7. Article
  8. NovelAntimicrobial agents and chemotherapy · 2025
    Article
  9. Genetic diversity ofMalariaWorld journal · 2025
    Article
  10. Article
  11. Application of a new highly multiplexed amplicon sequencing tool to evaluatemedRxiv : the preprint server for health sciences · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Profiling antimalarial drug-resistant haplotypes inTherapeutic advances in infectious disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Elangwe M Sarah-Matio *MIVEGEC, Université de Montpellier, CNRS, IRD, Montpellier, France.
Emilie Guillochon *Université de Paris, MERIT, IRD, Paris, France.
Sandrine E NsangoMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
Luc AbateMIVEGEC, Université de Montpellier, CNRS, IRD, Montpellier, France.
Christelle M NgouMIVEGEC, Université de Montpellier, CNRS, IRD, Montpellier, France.
Gaelle A BouopdaMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
Lionel B Feufack-DonfackMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
Albert N BayibékiUniversité Catholique d'Afrique Centrale, Yaoundé, Cameroon.
Majoline Tchioffo TsapiMIVEGEC, Université de Montpellier, CNRS, IRD, Montpellier, France.
Arthur TalmanMIVEGEC, Université de Montpellier, CNRS, IRD, Montpellier, France.
Alejandro Marin-MenendezMIVEGEC, Université de Montpellier, CNRS, IRD, Montpellier, France.
Lawrence AyongMalaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon.
Antoine ClaessensMIVEGEC, Université de Montpellier, CNRS, IRD, Montpellier, France.
Thierry LefèvreMIVEGEC, Université de Montpellier, CNRS, IRD, Montpellier, France.
Antoine Berry *Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Université Toulouse, CNRS UMR5051, INSERM UMR1291, UPS, Toulouse, France.ORCID 0000-0002-6626-7766
Isabelle Morlais *MIVEGEC, Université de Montpellier, CNRS, IRD, Montpellier, France.ORCID 0000-0002-2962-7670
Centre National de la Recherche Scientifique · FRCentre Pasteur du Cameroun · CMUniversity of Douala · CMCatholic University of Central Africa · CMUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria control relies on passive case detection, and this strategy fails detecting asymptomatic infections. In addition, infections in endemic areas harbor multiple parasite genotypes that could affect case management and malaria epidemiology. Here, we performed AmpSeq genotyping to capture polymorphisms associated with antimalarial resistance and the genetic diversity within natural Plasmodium falciparum infections. Known genetic polymorphisms associated with altered drug susceptibility were screened for the five most common marker genes,

Indexed as

AntimalarialsFolic Acid AntagonistsMalariaMalaria, FalciparumAsymptomatic InfectionsChloroquineDrug ResistanceGenotypeHumansMutationPlasmodium falciparumProtozoan ProteinsAntimalarialsChloroquineFolic Acid AntagonistsProtozoan Proteinsantimalarial drug resistanceCameroongenetic diversitymolecular genotypingPlasmodium falciparumsymptomatic and asymptomatic carriers

Identifiers

PMID35862750
PMCPMC9380546
OpenAlexW4283832134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.