Evidence map›Paper›PMID 35862648›Full record

ArticleAmerican journal of physiology. Renal physiology2022

Small hairpin inhibitory RNA delivery in the metanephric organ culture identifies long noncoding RNA

Kara Eckberg, Ivan Weisser, Daniel Buttram, Nikunj Somia, Peter Igarashi, Karam S Aboudehen

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Long Noncoding RNAs in the Pathogenesis of Insulin Resistance.International journal of molecular sciences · 2022
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kara EckbergDepartment of Medicine, University of Minnesota, Minneapolis, Minnesota.
Ivan WeisserDepartment of Medicine, University of Minnesota, Minneapolis, Minnesota.
Daniel ButtramDepartment of Medicine, University of Minnesota, Minneapolis, Minnesota.
Nikunj SomiaDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota.
Peter IgarashiDepartment of Medicine, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0001-8698-1185
Karam S AboudehenDepartment of Medicine, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0003-4975-464X
University of Minnesota · US

Funding

REGULATION OF RENAL NA+/H+ EXCHANGER GENE EXPRESSIONR01DK042921 · NIDDK · YALE UNIVERSITY · PI IGARASHI, PETER · 1991 to 2025
$5.1M
Regulation of Kidney-Specific Gene ExpressionR37DK042921 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI IGARASHI, PETER · 2011 to 2020
$3.6M
Deregulation of Long Noncoding RNA in the Pathogenesis of Autosomal Dominant Polycystic Kidney DiseaseK01DK116934 · NIDDK · UNIVERSITY OF MINNESOTA · PI ABOUDEHEN, KARAM · 2019 to 2023
$544k
NIDDK NIH HHS K01 DK116934NIDDK NIH HHS R01 DK042921NIDDK NIH HHS R37 DK042921
6 · The paper itself

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is a monogenic disorder characterized by the formation of kidney cysts that originate from the epithelial tubules of the nephron and primarily results from mutations in polycystin-1 (

Indexed as

CystsPolycystic Kidney, Autosomal DominantRNA, Long NoncodingAnimalsHumansKidneyMiceOrgan Culture TechniquesPolycystic Kidney DiseasesRNA, Small InterferingTRPP Cation ChannelsRNA, Long NoncodingRNA, Small InterferingTRPP Cation Channelsc-MYCmetanephric organ culturepolycystic kidney diseasePvt1self-complementary adeno-associated virus

Identifiers

PMID35862648
PMCPMC9423782
OpenAlexW4286208125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.