Evidence map›Paper›PMID 35862520›Full record

ArticleScience (New York, N.Y.)2022

A chromosomal inversion contributes to divergence in multiple traits between deer mouse ecotypes.

Emily R Hager, Olivia S Harringmeyer, T Brock Wooldridge, Shunn Theingi, Jacob T Gable, Sade McFadden, Beverly Neugeboren, Kyle M Turner, Jeffrey D Jensen, Hopi E Hoekstra

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Ancient DNA from shells reveals delayed genomic erosion and rapid immune adaptation in the critically endangered black abalone.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Article
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  11. Rapid centromere turnover and the adaptive radiation of lemurs.bioRxiv : the preprint server for biology · 2026
    Article
  12. Article
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  14. Article
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  19. Ancestral and local adaptation contribute to dispersal out of the Qinghai-Tibet Plateau in a bumblebee.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emily R Hager *Department of Molecular and Cellular Biology, Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, and Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0001-7873-2779
Olivia S Harringmeyer *Department of Molecular and Cellular Biology, Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, and Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0003-4040-2226
T Brock WooldridgeDepartment of Molecular and Cellular Biology, Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, and Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0003-3629-0495
Shunn TheingiDepartment of Molecular and Cellular Biology, Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, and Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0002-8886-3163
Jacob T GableDepartment of Molecular and Cellular Biology, Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, and Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0001-6906-1571
Sade McFaddenDepartment of Molecular and Cellular Biology, Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, and Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0003-0192-6684
Beverly NeugeborenDepartment of Molecular and Cellular Biology, Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, and Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0003-3127-9369
Kyle M TurnerDepartment of Molecular and Cellular Biology, Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, and Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0002-7990-1842
Jeffrey D JensenSchool of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.ORCID 0000-0002-4786-8064
Hopi E HoekstraDepartment of Molecular and Cellular Biology, Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, and Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA.ORCID 0000-0003-1431-1769

Funding

Training in Molecular, Cellular, and Chemical BiologyT32GM007598 · NIGMS · HARVARD UNIVERSITY · PI DULAC, CATHERINE · 1985 to 2019
$16.2M
MOLECULAR BIOPHYSICS TRAINING GRANTT32GM008313 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MURTHY, VENKATESH N · 1989 to 2023
$14.6M
On differentiating selective and neutral evolutionary processesR35GM139383 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI JENSEN, JEFFREY D · 2021 to 2025
$3.0M
Howard Hughes Medical InstituteNIGMS NIH HHS R35 GM139383NIGMS NIH HHS T32 GM007598NIGMS NIH HHS T32 GM008313
6 · The paper itself

Abstract

How locally adapted ecotypes are established and maintained within a species is a long-standing question in evolutionary biology. Using forest and prairie ecotypes of deer mice (

Indexed as

Chromosome InversionEcotypePeromyscusAnimalsGene FlowRecombination, Genetic

Identifiers

PMID35862520
PMCPMC9571565

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.