Evidence map›Paper›PMID 35862456›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Activity-dependent endoplasmic reticulum Ca

Lauren C Panzera, Ben Johnson, Josiah A Quinn, In Ha Cho, Michael M Tamkun, Michael B Hoppa

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Visual input drives diverse ER calcium signals in neuronsbioRxiv : the preprint server for biology · 2025
    Article
  4. Ion channels and actin: A tale of two friends.Histology and histopathology · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. The Endoplasmic Reticulum and Its Contacts: Emerging Roles in Axon Development, Neurotransmission, and Degeneration.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. NPC1-dependent alterations in KNature communications · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lauren C PanzeraDepartment of Biology, Dartmouth College, Hanover, NH 03755.ORCID 0000-0001-8519-039X
Ben JohnsonDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523.
Josiah A QuinnDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523.ORCID 0000-0002-8852-4006
In Ha ChoDepartment of Biology, Dartmouth College, Hanover, NH 03755.ORCID 0000-0002-1404-7681
Michael M TamkunDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523.ORCID 0000-0002-0455-6167
Michael B HoppaDepartment of Biology, Dartmouth College, Hanover, NH 03755.ORCID 0000-0003-2340-0915
Colorado State University · USDartmouth College · US

Funding

Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI LACEFIELD, SONI · 2016 to 2025
$25.9M
Neuronal Cell Biology of Kv2.1-induced Endoplasmic Reticulum/Plasma Membrane Contact sitesR01NS112365 · NINDS · COLORADO STATE UNIVERSITY · PI HOPPA, MICHAEL BLAKE, TAMKUN, MICHAEL M. · 2020 to 2024
$2.0M
The Action Potential as a Modulator of Synaptic TransmissionF31NS110192 · NINDS · DARTMOUTH COLLEGE · PI PANZERA, LAUREN C · 2019 to 2020
$91k
NIGMS NIH HHS P20 GM113132NINDS NIH HHS F31 NS110192NINDS NIH HHS R01 NS112365
6 · The paper itself

Abstract

The endoplasmic reticulum (ER) forms a continuous and dynamic network throughout a neuron, extending from dendrites to axon terminals, and axonal ER dysfunction is implicated in several neurological disorders. In addition, tight junctions between the ER and plasma membrane (PM) are formed by several molecules including Kv2 channels, but the cellular functions of many ER-PM junctions remain unknown. Recently, dynamic Ca

Indexed as

Endoplasmic ReticulumShab Potassium ChannelsCalciumCalcium SignalingCell MembraneNeuronsSynaptic TransmissionCalciumShab Potassium Channelscalciumendoplasmic reticulumexocytosisKv2synaptic transmission

Identifiers

PMID35862456
PMCPMC9335237
OpenAlexW4286499435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.