Evidence map›Paper›PMID 35862175›Full record

ArticleJournal of the American Heart Association2022

Incidence of Preclinical Heart Failure in a Community Population.

Kathleen A Young, Christopher G Scott, Richard J Rodeheffer, Horng H Chen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07185100 (A Prospective, Cross-sectional, Nationwide Community-based Observational Study to Determine the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07185100 recruitingnot on this mapstarted 2025, after this paper: background citation

A Prospective, Cross-sectional, Nationwide Community-based Observational Study to Determine the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR

TypeobservationalSponsorGerman Heart InstituteRan2025 to 2036Enrolled600ConditionsHeart Failure With Preserved Ejection Fraction (HFPEF), Renal Dysfunction, Stage B Heart Failure
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Association of Impaired Relaxation Mitral Inflow Pattern (Grade 1 Diastolic Function) With Long-Term Noncardiovascular and Cardiovascular Mortality.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kathleen A YoungDepartment of Cardiovascular Diseases Mayo Clinic Rochester MN United States.ORCID 0000-0002-7071-192X
Christopher G ScottDivision of Biomedical Statistics and Informatics Mayo Clinic Rochester MN United States.ORCID 0000-0003-1340-0647
Richard J RodehefferDepartment of Cardiovascular Diseases Mayo Clinic Rochester MN United States.
Horng H ChenDepartment of Cardiovascular Diseases Mayo Clinic Rochester MN United States.ORCID 0000-0002-2315-0330
Mayo Clinic · US

Funding

Recruitment and Phenotyping CoreP01HL076611 · NHLBI · MAYO CLINIC ROCHESTER · PI BURNETT, JOHN C · 2005 to 2015
$19.6M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Human Cardiorenal SyndromeR01HL084155 · NHLBI · MAYO CLINIC ROCHESTER · PI HORNG H CHEN · 2009 to 2026
$5.5M
Preclinical Diastolic Dysfunction in Type 2 DiabetesR01HL136440 · NHLBI · MAYO CLINIC ROCHESTER · PI CHEN, HORNG H · 2018 to 2021
$2.8M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
NHLBI NIH HHS P01 HL076611NHLBI NIH HHS R01 HL084155NHLBI NIH HHS R01 HL136440NIA NIH HHS R01 AG034676NIA NIH HHS R33 AG058738
6 · The paper itself

Abstract

Background A high prevalence of preclinical heart failure (HF) (Stages A and B) has previously been shown. The aim of this study was to explore factors associated with the incidence of preclinical HF in a community population. Methods and Results Retrospective review of 393 healthy community individuals aged ≥45 years from the Olmsted County Heart Function Study that returned for 2 visits, 4 years apart. At visit 2, individuals that remained normal were compared with those that developed preclinical HF. By the second visit, 191 (49%) developed preclinical HF (12.1 cases per 100 person-years of follow-up); 65 (34%) Stage A and 126 (66%) Stage B. Those that developed preclinical HF (n=191) were older (

Indexed as

Heart FailureHypertensionBiomarkersEchocardiographyHumansIncidenceNatriuretic Peptide, BrainObesityPeptide FragmentsBiomarkersNatriuretic Peptide, BrainPeptide Fragmentsincidencenatural historypreclinical heart failure

Identifiers

PMID35862175
PMCPMC9375502
OpenAlexW4285987985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.