Evidence map›Paper›PMID 35862003›Full record

ArticleCirculation. Cardiovascular quality and outcomes2022

County-Level Social Vulnerability is Associated With In-Hospital Death and Major Adverse Cardiovascular Events in Patients Hospitalized With COVID-19: An Analysis of the American Heart Association COVID-19 Cardiovascular Disease Registry.

Shabatun J Islam, Gargya Malla, Robert W Yeh, Arshed A Quyyumi, Dhruv S Kazi, Wei Tian, Yang Song, Aditi Nayak, Anurag Mehta, Yi-An Ko and 4 more

Abstract read
In one paragraph

Article in Circulation. Cardiovascular quality and outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

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0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
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  3. Associations Between Neighborhood Social Vulnerability and the Distribution of Rhinologists in the United States.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
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  17. Protective effect of vaccination on the risk of cardiovascular disease after SARS-CoV-2 infection.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Article
  18. Article
  19. Collaborating for COVID-19: Hospital Health Information Exchange and Public Health Partnership.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2024
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Shabatun J IslamDepartment of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA (S.J.I., A.A.Q., A.N., A.M., Y.-A.K., A.G.).ORCID 0000-0002-0886-9021
Gargya MallaDepartment of Epidemiology, University of Alabama at Birmingham (G.M.).ORCID 0000-0003-0156-3254
Robert W YehRichard A. and Susan F. Smith Center for Outcomes Research, Beth Israel Deaconess Medical Center, Boston, MA (R.W.Y., D.S.K., W.T., Y.S., R.K.W.).
Arshed A QuyyumiDepartment of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA (S.J.I., A.A.Q., A.N., A.M., Y.-A.K., A.G.).ORCID 0000-0002-8166-679X
Dhruv S KaziRichard A. and Susan F. Smith Center for Outcomes Research, Beth Israel Deaconess Medical Center, Boston, MA (R.W.Y., D.S.K., W.T., Y.S., R.K.W.).ORCID 0000-0002-9510-2979
Wei TianRichard A. and Susan F. Smith Center for Outcomes Research, Beth Israel Deaconess Medical Center, Boston, MA (R.W.Y., D.S.K., W.T., Y.S., R.K.W.).ORCID 0000-0002-8095-8993
Yang SongRichard A. and Susan F. Smith Center for Outcomes Research, Beth Israel Deaconess Medical Center, Boston, MA (R.W.Y., D.S.K., W.T., Y.S., R.K.W.).
Aditi NayakDepartment of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA (S.J.I., A.A.Q., A.N., A.M., Y.-A.K., A.G.).ORCID 0000-0002-6986-0987
Anurag MehtaDepartment of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA (S.J.I., A.A.Q., A.N., A.M., Y.-A.K., A.G.).
Yi-An KoDepartment of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA (S.J.I., A.A.Q., A.N., A.M., Y.-A.K., A.G.).ORCID 0000-0002-6543-9765
James A de LemosDepartment of Medicine, Division of Cardiology, UT Southwestern Medical Center, Dallas, TX (J.A.d.L.).ORCID 0000-0003-2211-7261
Fatima RodriguezDivision of Cardiovascular Medicine, Stanford University, CA (F.R.).ORCID 0000-0002-5226-0723
Abhinav GoyalDepartment of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA (S.J.I., A.A.Q., A.N., A.M., Y.-A.K., A.G.).
Rishi K WadheraDepartment of Epidemiology, University of Alabama at Birmingham (G.M.).

Funding

Cardiovascular Health of Low-Income Working-Age Adults in the US: Health Care Access, Policy, and the PandemicR01HL164561 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Rishi Kumar Wadhera · 2022 to 2026
$3.7M
A Multi-Dimensional Linked Registry to Identify Biological, Clinical, Health System, and Socioeconomic Risk Factors for COVID-19-Related Cardiovascular EventsR01HL157530 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GERSZTEN, ROBERT E, KAZI, DHRUV SATISH · 2021 to 2024
$3.0M
Explaining Rising Heart Failure Mortality in MedicareK23HL148525 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI WADHERA, RISHI KUMAR · 2019 to 2023
$863k
NHLBI NIH HHS K23 HL148525NHLBI NIH HHS R01 HL157530NHLBI NIH HHS R01 HL164561
6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic has disproportionately affected low-income and racial/ethnic minority populations in the United States. However, it is unknown whether hospitalized patients with COVID-19 from socially vulnerable communities experience higher rates of death and/or major adverse cardiovascular events (MACEs). Thus, we evaluated the association between county-level social vulnerability and in-hospital mortality and MACE in a national cohort of hospitalized COVID-19 patients.

methodsOur study population included patients with COVID-19 in the American Heart Association COVID-19 Cardiovascular Disease Registry across 107 US hospitals between January 14, 2020 to November 30, 2020. The Social Vulnerability Index (SVI), a composite measure of community vulnerability developed by Centers for Disease Control and Prevention, was used to classify the county-level social vulnerability of patients' place of residence. We fit a hierarchical logistic regression model with hospital-level random intercepts to evaluate the association of SVI with in-hospital mortality and MACE.

resultsAmong 16 939 hospitalized COVID-19 patients in the registry, 5065 (29.9%) resided in the most vulnerable communities (highest national quartile of SVI). Compared with those in the lowest quartile of SVI, patients in the highest quartile were younger (age 60.2 versus 62.3 years) and more likely to be Black adults (36.7% versus 12.2%) and Medicaid-insured (31.1% versus 23.0%). After adjustment for demographics (age, sex, race/ethnicity) and insurance status, the highest quartile of SVI (compared with the lowest) was associated with higher likelihood of in-hospital mortality (OR, 1.25 [1.03-1.53];

conclusionsPatients hospitalized with COVID-19 residing in more socially vulnerable communities experienced higher rates of in-hospital mortality and MACE, independent of race, ethnicity, and several clinical factors. Clinical and health system strategies are needed to improve health outcomes for socially vulnerable patients.

Indexed as

Cardiovascular DiseasesCOVID-19AdultAmerican Heart AssociationEthnicityHospital MortalityHumansMiddle AgedMinority GroupsPandemicsRegistriesSocial VulnerabilityUnited Statescardiovascular outcomesCOVID-19ethnicityhealth disparitiespandemic

Identifiers

PMID35862003
PMCPMC9387665

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.