Evidence map›Paper›PMID 35861895›Full record

ArticleActa parasitologica2022

Successful Treatment of Primary Amoebic Meningoencephalitis Using a Novel Therapeutic Regimen Including Miltefosine and Voriconazole.

Dalila Y Martínez, Fanny Bravo-Cossio, María Del Carmen Valdivia-Tapia, Nilton Yhuri Carreazo, Alfonso M Cabello-Vilchez

Abstract readCase Reports
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In one paragraph

Article in Acta parasitologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  4. Approaches for TargetingPathogens (Basel, Switzerland) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Dalila Y MartínezInstituto de Medicina Tropical "Alexander Von Humboldt", Universidad Peruana Cayetano Heredia, Lima, Perú.
Fanny Bravo-CossioHospital de Emergencias Pediátricas, Lima, Perú.
María Del Carmen Valdivia-TapiaHospital de Emergencias Pediátricas, Lima, Perú.
Nilton Yhuri CarreazoHospital de Emergencias Pediátricas, Lima, Perú. yhuroc@gmail.com.ORCID http://orcid.org/0000-0002-5269-4855
Alfonso M Cabello-VilchezInstituto de Medicina Tropical "Alexander Von Humboldt", Universidad Peruana Cayetano Heredia, Lima, Perú.
Universidad Peruana Cayetano Heredia · PEHospital Nacional Dos de Mayo · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genus Naegleria consists of free-living amoebae widely distributed worldwide in soil and freshwater habitats. Primary amoebic meningoencephalitis (PAM) is an uncommon and most likely fatal disease. The incubation period is approximately 7 days. The first symptoms are headache, nasal congestion, fever, vomiting, stiff neck within 3-4 days after the first symptoms, confusion, abnormal behavior, seizures, loss of balance and body control, coma, and death. We describe the case of a child who presented with PAM due to Naegleria sp., fully recovered from the infection without apparent sequels after treatment with a regimen that included miltefosine and voriconazole.

Indexed as

AmebiasisCentral Nervous System Protozoal InfectionsNaegleriaNaegleria fowleriChildHumansPhosphorylcholineVoriconazolemiltefosinePhosphorylcholineVoriconazoleCentral nervous system protozoal infectionsChildMiltefosineNaegleriaVoriconazole

Identifiers

PMID35861895
OpenAlexW4286492852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.