Evidence map›Paper›PMID 35861862›Full record

ArticleInternational journal of colorectal disease2022

Computer-aided diagnosis of serrated colorectal lesions using non-magnified white-light endoscopic images.

Daiki Nemoto, Zhe Guo, Boyuan Peng, Ruiyao Zhang, Yuki Nakajima, Yoshikazu Hayashi, Takeshi Yamashina, Masato Aizawa, Kenichi Utano, Alan Kawarai Lefor and 2 more

Abstract read
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In one paragraph

Article in International journal of colorectal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Computer-aided diagnosis for colorectal polyp in comparison with endoscopists: Systematic review and meta-analysis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Daiki NemotoDepartment of Coloproctology & Gastroenterology, Aizu Medical Center, Fukushima Medical University, 21-2 Maeda, Tanisawa, Aizuwakamatsu, Fukushima, 969-3492, Japan.
Zhe GuoBiomedical Information Engineering Lab, The University of Aizu, Aizuwakamatsu, Fukushima, Japan.
Boyuan PengBiomedical Information Engineering Lab, The University of Aizu, Aizuwakamatsu, Fukushima, Japan.
Ruiyao ZhangBiomedical Information Engineering Lab, The University of Aizu, Aizuwakamatsu, Fukushima, Japan.
Yuki NakajimaDepartment of Coloproctology & Gastroenterology, Aizu Medical Center, Fukushima Medical University, 21-2 Maeda, Tanisawa, Aizuwakamatsu, Fukushima, 969-3492, Japan.
Yoshikazu HayashiDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Takeshi YamashinaGastroenterology and Hepatology, Kansai Medical University Medical Center, Moriguchi, Osaka, Japan.
Masato AizawaDepartment of Coloproctology & Gastroenterology, Aizu Medical Center, Fukushima Medical University, 21-2 Maeda, Tanisawa, Aizuwakamatsu, Fukushima, 969-3492, Japan.
Kenichi UtanoDepartment of Coloproctology & Gastroenterology, Aizu Medical Center, Fukushima Medical University, 21-2 Maeda, Tanisawa, Aizuwakamatsu, Fukushima, 969-3492, Japan.
Alan Kawarai LeforDepartment of Surgery, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Xin ZhuBiomedical Information Engineering Lab, The University of Aizu, Aizuwakamatsu, Fukushima, Japan.
Kazutomo TogashiDepartment of Coloproctology & Gastroenterology, Aizu Medical Center, Fukushima Medical University, 21-2 Maeda, Tanisawa, Aizuwakamatsu, Fukushima, 969-3492, Japan. togashik@fmu.ac.jp.ORCID http://orcid.org/0000-0002-4080-5335
Fukushima Medical University · JPUniversity of Aizu · JPJichi Medical University · JPKansai Medical University · JP

Funding

Competitive Research Fund of the University of Aizu 2019-P-2MEXT/JSPS KAKENHI 18K08010
6 · The paper itself

Abstract

purposeComputer-aided diagnosis systems for polyp characterization are commercially available but cannot recognize subtypes of sessile lesions. This study aimed to develop a computer-aided diagnosis system to characterize polyps using non-magnified white-light endoscopic images.

methodsA total of 2249 non-magnified white-light images from 1030 lesions including 534 tubular adenomas, 225 sessile serrated adenoma/polyps, and 271 hyperplastic polyps in the proximal colon were consecutively extracted from an image library and divided into training and testing datasets (4:1), based on the date of colonoscopy. Using ResNet-50 networks, we developed a classifier (1) to differentiate adenomas from serrated lesions, and another classifier (2) to differentiate sessile serrated adenoma/polyps from hyperplastic polyps. Diagnostic performance was assessed using the testing dataset. The computer-aided diagnosis system generated a probability score for each image, and a probability score for each lesion was calculated as the weighted mean with a log

resultsThe area under the curve of classifier (1) for adenomas was equivalent to E1 and superior to E2 (classifier 86%, E1 86%, E2 69%; classifier vs. E2, p < 0.001). In contrast, the area under the curve of classifier (2) for sessile serrated adenoma/polyps was inferior to both experts (classifier 55%, E1 68%, E2 79%; classifier vs. E2, p < 0.001).

conclusionThe classifier (1) developed using white-light images alone compares favorably with experts in differentiating adenomas from serrated lesions. However, the classifier (2) to identify sessile serrated adenoma/polyps is inferior to experts.

Indexed as

AdenomaColonic PolypsColorectal NeoplasmsColonoscopyComputersHumansArtificial intelligenceColonic polypsColonoscopySerrated lesion

Identifiers

PMID35861862
OpenAlexW4286111386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.