Evidence map›Paper›PMID 35861660›Full record

ArticleACS chemical biology2022

Tandrila Das, Xinglin Yang, Hwayoung Lee, Emma H Garst, Estefania Valencia, Kartik Chandran, Wonpil Im, Howard C Hang

Open access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
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  6. Article
  7. Article
  8. mBio · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Cholesterol binding to VCAM-1 promotes vascular inflammation.bioRxiv : the preprint server for biology · 2024
    Article
  13. Review
  14. Review
  15. Article
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  17. Article
  18. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Tandrila DasLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.ORCID 0000-0002-3398-9877
Xinglin YangDepartment of Immunology and Microbiology, Scripps Research, La Jolla, California 92037, United States.
Hwayoung LeeDepartment of Biological Sciences, Chemistry, and Bioengineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States.ORCID 0000-0003-2332-1993
Emma H GarstLaboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States.ORCID 0000-0001-8170-2343
Estefania ValenciaDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Kartik ChandranDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Wonpil ImDepartment of Biological Sciences, Chemistry, and Bioengineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States.ORCID 0000-0001-5642-6041
Howard C HangDepartment of Immunology and Microbiology, Scripps Research, La Jolla, California 92037, United States.ORCID 0000-0003-4053-5547
Scripps Institution of Oceanography · USAlbert Einstein College of Medicine · USLehigh University · USTri-Institutional PhD Program in Chemical Biology · US

Funding

Studies on Protein LipidationR01GM087544 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI HANG, HOWARD C · 2010 to 2023
$4.4M
Host-virus interactions in the control of filovirus entryR01AI134824 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CHANDRAN, KARTIK · 2018 to 2021
$1.9M
NIAID NIH HHS R01 AI134824NIGMS NIH HHS R01 GM087544
6 · The paper itself

Abstract

Interferon-induced transmembrane proteins (IFITM1, 2, and 3) are important antiviral proteins that are active against many viruses, including influenza A virus (IAV), dengue virus (DENV), Ebola virus (EBOV), Zika virus (ZIKV), and severe acute respiratory syndrome coronavirus (SARS-CoV). IFITM proteins exhibit specificity in activity, but their distinct mechanisms of action and regulation are unclear. Since

Indexed as

Antiviral AgentsLipoylationMembrane ProteinsSterolsAnimalsCholesterolInfluenza A virusSARS-CoV-2Zika VirusAntiviral AgentsCholesterolMembrane ProteinsSterols

Identifiers

PMID35861660
PMCPMC10597057
OpenAlexW4286111646

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.