Evidence map›Paper›PMID 35861539›Full record

ArticleAntimicrobial agents and chemotherapy2022

Activity of Exebacase (CF-301) against Biofilms Formed by Staphylococcus epidermidis Strains Isolated from Prosthetic Joint Infections.

Aubin Souche, Camille Kolenda, Jordan Teoli, Raymond Schuch, Tristan Ferry, Frédéric Laurent, Jérôme Josse

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Beneficial perspective onFrontiers in immunology · 2025
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Aubin SoucheCIRI-Centre International de Recherche en Infectiologie, Inserm, U1111, CNRS UMR5308, ENS de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Camille KolendaCIRI-Centre International de Recherche en Infectiologie, Inserm, U1111, CNRS UMR5308, ENS de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Jordan TeoliUniversité Claude Bernard Lyon 1, Lyon, France.
Raymond SchuchContraFect Corporation, Yonkers, New York, USA.ORCID 0000-0003-4324-573X
Tristan FerryCIRI-Centre International de Recherche en Infectiologie, Inserm, U1111, CNRS UMR5308, ENS de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Frédéric LaurentCIRI-Centre International de Recherche en Infectiologie, Inserm, U1111, CNRS UMR5308, ENS de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Jérôme JosseCIRI-Centre International de Recherche en Infectiologie, Inserm, U1111, CNRS UMR5308, ENS de Lyon, Université Claude Bernard Lyon 1, Lyon, France.ORCID 0000-0001-6780-9646
Université Claude Bernard Lyon 1 · FRContraFect (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Staphylococcus epidermidis is one of the main pathogens responsible for bone and joint infections, especially those involving prosthetic materials, due to its ability to form biofilms. In these cases, biofilm formation, combined with increased antimicrobial resistance, often results in therapeutic failures. In this context, the development of innovative therapies active against S. epidermidis is a priority. The aim of this study was to evaluate the

Indexed as

DaptomycinStaphylococcal InfectionsAnti-Bacterial AgentsBiofilmsEndopeptidasesHumansMicrobial Sensitivity TestsRifampinStaphylococcus epidermidisVancomycinAnti-Bacterial AgentsDaptomycinEndopeptidasesexebacaseRifampinVancomycinbiofilmsCF-301exebacaseprosthetic joint infectionsStaphylococcus epidermidis

Identifiers

PMID35861539
PMCPMC9380561
OpenAlexW4285009123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.