Evidence map›Paper›PMID 35861521›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2022

Satellite cell depletion does not affect diaphragm adaptations to hypoxia.

Nicholas T Thomas, Amy L Confides, Christopher S Fry, Esther E Dupont-Versteegden

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicholas T ThomasCenter for Muscle Biology, University of Kentucky, Lexington, Kentucky.ORCID 0000-0003-4578-8463
Amy L ConfidesCenter for Muscle Biology, University of Kentucky, Lexington, Kentucky.
Christopher S FryCenter for Muscle Biology, University of Kentucky, Lexington, Kentucky.ORCID 0000-0002-4207-6594
Esther E Dupont-VersteegdenCenter for Muscle Biology, University of Kentucky, Lexington, Kentucky.ORCID 0000-0001-5576-9659
University of Kentucky · US

Funding

Effect of Satellite Cell Ablation on the Aging DiaphragmR21AG043721 · NIA · UNIVERSITY OF KENTUCKY · PI DUPONT-VERSTEEGDEN, ESTHER E · 2013 to 2014
$413k
NIA NIH HHS R21 AG043721
6 · The paper itself

Abstract

The diaphragm is the main skeletal muscle responsible for inspiration and is susceptible to age-associated decline in function and morphology. Satellite cells in diaphragm fuse into unperturbed muscle fibers throughout life, yet their role in adaptations to hypoxia in diaphragm is unknown. Given their continual fusion, we hypothesize that satellite cell depletion will negatively impact adaptations to hypoxia in the diaphragm, particularly with aging. We used the Pax7

Indexed as

Satellite Cells, Skeletal MuscleAdaptation, PhysiologicalAnimalsDiaphragmHypoxiaMaleMiceMuscle Fibers, SkeletalMuscle, SkeletalagingdiaphragmhypoxiaPax3satellite cells

Identifiers

PMID35861521
PMCPMC9448290
OpenAlexW4286111165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.